BAP1 Antibody (1G8) [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # NB110-60521B

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NB110-60521

Alexa Fluor 350

NB110-60521AF350

Alexa Fluor 405

NB110-60521AF405

Alexa Fluor 488

NB110-60521AF488

Alexa Fluor 532

NB110-60521AF532

Alexa Fluor 594

NB110-60521AF594

Alexa Fluor 647

NB110-60521AF647

Alexa Fluor 700

NB110-60521AF700

Alexa Fluor 750

NB110-60521AF750

Allophycocyanin

NB110-60521APC

CoraFluor 1

NB110-60521CL1

DyLight 350

NB110-60521UV

DyLight 405

NB110-60521V

DyLight 488

NB110-60521G

DyLight 550

NB110-60521R

DyLight 594

NB110-60521DL594

DyLight 650

NB110-60521C

DyLight 680

NB110-60521FR

DyLight 755

NB110-60521IR

FITC

NB110-60521F

HRP

NB110-60521H

Janelia Fluor 525

NB110-60521JF525

Janelia Fluor 549

NB110-60521JF549

Janelia Fluor 646

NB110-60521JF646

Janelia Fluor 669

NB110-60521JF669

mFluor Violet 450 SE

NB110-60521MFV450

mFluor Violet 500 SE

NB110-60521MFV500

mFluor Violet 610 SE

NB110-60521MFV610

PE

NB110-60521PE

Forumulation

Catalog #

Azide and BSA Free

NBP2-80589

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Western Blot

Label

Biotin

Antibody Source

Monoclonal Mouse IgG₁ kappa Clone # 1G8

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all BAP1 Antibodies »

Product Specifications

Immunogen

Full-length human BAP1 protein expressed and purified from E.coli. [UniProt# Q92560]

Epitope

Within the UCH domain of BAP1.

Localization

Nuclear

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁ kappa

Applications for BAP1 Antibody (1G8) [Biotin]

Application

Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: BAP1

Mutations within the BRCA1 gene, localized to chromosome 17q, are believed to account for approximately 45% of families with increased incidence of both early-onset breast cancer and ovarian cancer. The BRCA1 gene is expressed in numerous tissues, including breast and ovary, and encodes a predicted protein of 1863 amino acids. This protein contains a RING domain near the N-terminus and appears to encode a tumor suppressor. BARD1 (BRCA1-associated RING domain protein 1) and BAP1 (BRCA1-associated protein 1) have both been shown to bind to the N-terminus of BRCA1 and are potential mediators of tumor suppression. BARD1 contains an N-terminal RING domain and three tandem ankyrin repeats. The C-terminus of BARD1 contains a region with sequence homology to BRCA1, termed the BRCT domain. BAP1 is a ubiquitin hydrolase and has been shown to enhance BRCA1-mediated cell growth suppression.

Long Name

BRCA1-associated protein 1

Alternate Names

Cerebral Protein-6, UCHL2

Gene Symbol

BAP1

Additional BAP1 Products

Product Documents for BAP1 Antibody (1G8) [Biotin]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for BAP1 Antibody (1G8) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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