BMP-15/GDF-9B Antibody (6K5C3)
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-16342
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Scientific Data Images for BMP-15/GDF-9B Antibody (6K5C3)
Western Blot: BMP-15/GDF-9B Antibody (6K5C3) [NBP3-16342]
Western Blot: BMP-15/GDF-9B Antibody (6K5C3) [NBP3-16342] - Western blot analysis of extracts of various cell lines, using BMP-15/GDF-9B Rabbit mAb (NBP3-16342) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3min.Western Blot: BMP-15/GDF-9B Antibody (6K5C3) [NBP3-16342]
Western Blot: BMP-15/GDF-9B Antibody (6K5C3) [NBP3-16342] - Western blot analysis of extracts of Rat ovary, using BMP-15/GDF-9B Rabbit mAb (NBP3-16342) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 3min.Applications for BMP-15/GDF-9B Antibody (6K5C3)
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Background: BMP-15/GDF-9B
BMPs are secreted signaling molecules that comprise a subfamily of the TGF-beta superfamily and were originally identified as regulators of cartilage and bone formation. There are at least 20 structurally and functionally related BMPs, most of which play roles in embryogenesis and morphogenesis of various tissues and organs. Biologically active BMPs are usually homodimers containing a characteristic cysteine knot structure. Heterodimers, BMP-2/BMP-7 and BMP-4/BMP-7 have also been suggested to exist and function in vivo. They are more potent inducers of bone formation than their respective homodimers. In addition, heterodimers, but not homodimers, are ventral mesoderm inducers. Heterodimer activity may be mediated by a different or additional receptor subtype.
Decapentaplegic (Dpp) is one of at least five TGF-beta superfamily ligands identified in the Drosophila genome. Dpp, a functional ortholog of mammalian BMP-2 and BMP-4, is a morphogen and plays an essential role in Drosophila development. Dpp regulates embryonic dorsal-ventral polarity and is required for gut morphogenesis and outgrowth and patterning of imaginal disks.
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Additional BMP-15/GDF-9B Products
Product Documents for BMP-15/GDF-9B Antibody (6K5C3)
Product Specific Notices for BMP-15/GDF-9B Antibody (6K5C3)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.