BMP-15/GDF-9B Products
BMP-15 (Bone morphogenetic protein 15), also known as GDF-9B, is a TGF-b superfamily ligand that is expressed by oocytes throughout folliculogenesis and plays an important role in oocyte development. BMP-15 promotes the FSH-independent proliferation of ovarian granulosa cells (GC) and induces GC glycolysis and cholesterol synthesis.
BMP-15 blocks the FSH-induced GC expression of FSH R and multiple steroidogenic molecules. BMP-15 exerts is effects through interactions with BMPR-IB/ALK6 and BMPR-II, and nonphosphorylated BMP-15 functions as a competitive antagonist at BMPR-IB. Mature BMP-15 forms 34 kDa noncovalently-linked homodimers and 37 kDa heterodimers with mature GDF-9.
Products:
94 results for "BMP-15/GDF-9B" in Products
94 results for "BMP-15/GDF-9B" in Products
BMP-15/GDF-9B Products
BMP-15 (Bone morphogenetic protein 15), also known as GDF-9B, is a TGF-b superfamily ligand that is expressed by oocytes throughout folliculogenesis and plays an important role in oocyte development. BMP-15 promotes the FSH-independent proliferation of ovarian granulosa cells (GC) and induces GC glycolysis and cholesterol synthesis.
BMP-15 blocks the FSH-induced GC expression of FSH R and multiple steroidogenic molecules. BMP-15 exerts is effects through interactions with BMPR-IB/ALK6 and BMPR-II, and nonphosphorylated BMP-15 functions as a competitive antagonist at BMPR-IB. Mature BMP-15 forms 34 kDa noncovalently-linked homodimers and 37 kDa heterodimers with mature GDF-9.
Products:
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #BMP15/4263 |
Applications: | WB, ELISA |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #BMP15/4263 |
Applications: | WB, ELISA |
Source: | CHO |
Accession #: | O95972 |
Applications: | BA |
Reactivity: | Human |
Details: | Rat IgG2a Monoclonal Clone #317809 |
Applications: | WB, IHC |
Reactivity: | Mouse |
Details: | Rat IgG2a Monoclonal Clone #582703 |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #6K5C3 |
Applications: | WB |
Reactivity: | Mouse, Rat |
Details: | Sheep IgG Polyclonal |
Applications: | WB |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #SR1868 |
Applications: | WB, Flow |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA |
Applications: | ELISA |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #28A |
Applications: | WB, ELISA |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #28A |
Applications: | WB, ELISA |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #BMP15/4263 |
Applications: | WB, ELISA |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #BMP15/4263 |
Applications: | WB, ELISA |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #BMP15/4263 |
Applications: | WB, ELISA |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #BMP15/4263 |
Applications: | WB, ELISA |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #BMP15/4263 |
Applications: | WB, ELISA |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #BMP15/4263 |
Applications: | WB, ELISA |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #BMP15/4263 |
Applications: | WB, ELISA |