Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI6B7

Concentration

0.42 mg/ml

View all BMP-4 Antibodies »

Product Specifications

Immunogen

Recombinant fragment expressed in E.coli corresponding to amino acids 293-408 of human BMP4

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Specificity

This antibody is specific for Homo sapiens bone morphogenetic protein 4 (BMP4), transcript variant 2.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

46.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for BMP-4 Antibody (OTI6B7)

Western Blot: BMP-4 Antibody (OTI6B7) [NBP1-47666]

Western Blot: BMP-4 Antibody (OTI6B7) [NBP1-47666]

Western Blot: BMP-4 Antibody (6B7) [NBP1-47666] - BMP4 antibody ( 6B7 ) at 1:100000 dilution + Recombinant human BMP4.
Immunocytochemistry/ Immunofluorescence: BMP-4 Antibody (OTI6B7) [NBP1-47666]

Immunocytochemistry/ Immunofluorescence: BMP-4 Antibody (OTI6B7) [NBP1-47666]

Immunocytochemistry/Immunofluorescence: BMP-4 Antibody (6B7) [NBP1-47666] - Staining of HeLa cells transiently transfected by pCMV6-ENTRY BMP4.

Applications for BMP-4 Antibody (OTI6B7)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100

Western Blot

1:100000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

0.42 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: BMP-4

BMP4 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva.

Long Name

Bone Morphogenetic Protein 4

Alternate Names

BMP2B, BMP2B1, BMP4, MCOPS6, OFC11

Entrez Gene IDs

652 (Human)

Gene Symbol

BMP4

Additional BMP-4 Products

Product Documents for BMP-4 Antibody (OTI6B7)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for BMP-4 Antibody (OTI6B7)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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