BMP-4 Products
BMP-4 forms homodimers or heterodimers with BMP-2 and signals through receptor complexes composed of type I (primarily ActRIA or BMPR-IA) and type II (primarily ActRIIA or BMPR-II) receptors. BMP-4 plays an important role in mesenchyme formation, epidermal determination, suppression of neural induction, the development of multiple organs, and tissue repair. Compared to BMP-4 homodimers, BMP-4/BMP-7 heterodimers exhibit a greater potency in inducing osteogenic differentiation. The bioavailability of BMP-4 is regulated by its interaction with multiple proteins and glycosaminoglycans.
87 results for "BMP-4" in Products
87 results for "BMP-4" in Products
BMP-4 Products
BMP-4 forms homodimers or heterodimers with BMP-2 and signals through receptor complexes composed of type I (primarily ActRIA or BMPR-IA) and type II (primarily ActRIIA or BMPR-II) receptors. BMP-4 plays an important role in mesenchyme formation, epidermal determination, suppression of neural induction, the development of multiple organs, and tissue repair. Compared to BMP-4 homodimers, BMP-4/BMP-7 heterodimers exhibit a greater potency in inducing osteogenic differentiation. The bioavailability of BMP-4 is regulated by its interaction with multiple proteins and glycosaminoglycans.
| Source: | E. coli |
| Accession #: | P12644.1 |
| Applications: | BA |
Animal Free
| Source: | E. coli |
| Accession #: | P12644.1 |
| Applications: | BA |
Intended for preclinical researchers who may transition to GMP BMP-4 for their clinical work
| Source: | E. coli |
| Accession #: | P12644.1 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | Q53XC5 |
| Applications: | BA |
| Source: | CHO |
| Accession #: | P21275 |
| Applications: | BA |
| Sensitivity: | 3.68 pg/mL |
| Applications: | ELISA |
| Assay Range: | 31.2 - 2,000 pg/mL (Cell Culture Supernates, Bone Extracts) |
Selective ALK2 inhibitor
| Chemical Name: | 4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #66119 |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #100230 |
| Applications: | WB, Neut |
| Source: | E. coli |
| Accession #: | P12644 (BMP-4) & P18075 (BMP-7) |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
Potent BMP4 agonist
| Chemical Name: | 2-[[(4-Bromophenyl)methyl]thio]benzoxazole |
| Purity: | ≥99% (HPLC) |
| Assay Range: | 15.6 - 1,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #3C11C7 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +1 More |
![Western Blot: BMP-4 Antibody (3C11C7)BSA Free [NBP2-52424]](https://resources.bio-techne.com/images/products/BMP-4-Antibody-3C11C7-Western-Blot-NBP2-52424-img0009.jpg "Western Blot: BMP-4 Antibody (3C11C7)BSA Free [NBP2-52424]")
| Reactivity: | Human, Primate |
| Details: | Mouse IgG2b Monoclonal Clone #66110 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
Recombinant Monoclonal Antibody.
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #1128D |
| Applications: | WB, IHC |
| Reactivity: | Human, Primate |
| Details: | Mouse IgG1 Monoclonal Clone #66108 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC |
| Reactivity: | Zebrafish |
| Details: | Mouse IgG1 Monoclonal Clone #169125 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #65529 |
| Applications: | WB |
| Source: | E. coli |
| Accession #: | NP_571417 |
| Applications: | BA |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #JE42-44 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Mouse |
| Details: | Rat IgG1 Monoclonal Clone #871317 |
| Applications: | Neut |
