BMPR-IA/ALK-3 Antibody (002)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-90398

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP2-90398-100ul
NBP2-90398-50ul
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Key Product Details

Species Reactivity

Validated:

Mouse

Applications

ELISA

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 002

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all BMPR-IA/ALK-3 Antibodies »

Product Summary for BMPR-IA/ALK-3 Antibody (002)

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Mouse BMPR-IA/ALK-3 (Accession#: NP_033888.2; Met 1-Arg 152).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Applications for BMPR-IA/ALK-3 Antibody (002)

Application
Recommended Usage

ELISA

1:5000-1:10000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: BMPR-IA/ALK-3

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

Long Name

Bone Morphogenetic Protein Receptor IA/Activin Receptor-like Kinase 3

Alternate Names

ALK-3, BMPR1A, BMPRIA, CD292

Gene Symbol

BMPR1A

Additional BMPR-IA/ALK-3 Products

Product Documents for BMPR-IA/ALK-3 Antibody (002)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for BMPR-IA/ALK-3 Antibody (002)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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