The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

Long Name

Bone Morphogenetic Protein Receptor IA/Activin Receptor-like Kinase 3

Alternate Names

ALK-3, BMPR1A, BMPRIA, CD292

Gene Symbol

BMPR1A

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Product Documents for BMPR-IA/ALK-3 Antibody (002) [Janelia Fluor® 549]

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Product Specific Notices for BMPR-IA/ALK-3 Antibody (002) [Janelia Fluor® 549]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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BMPR-IA/ALK-3 Antibody (002) [Janelia Fluor® 549]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-90398JF549

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Applications for BMPR-IA/ALK-3 Antibody (002) [Janelia Fluor® 549]

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Background: BMPR-IA/ALK-3