Caspase-8 Antibody (1G12) [Janelia Fluor® 646]
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-80097JF646
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Validated:
Mouse
Applications
ELISA, Flow Cytometry, Immunohistochemistry, Western Blot
Label
Janelia Fluor 646
Antibody Source
Monoclonal Rat IgG1 kappa Clone # 1G12
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Summary for Caspase-8 Antibody (1G12) [Janelia Fluor® 646]
Immunogen
Recombinant mouse caspase-8 (p20 subunit).
Specificity
Recognizes the p20 subunit of mouse caspase-8. Detects bands of ~55kDa (full-length caspase-8) and ~18kDa (apoptosis-induced cleavage fragment) by Western blot. Does not cross-react with human caspase-8.
Clonality
Monoclonal
Host
Rat
Isotype
IgG1 kappa
Applications for Caspase-8 Antibody (1G12) [Janelia Fluor® 646]
Application
Recommended Usage
ELISA
Optimal dilutions of this antibody should be experimentally determined.
Flow Cytometry
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry
Optimal dilutions of this antibody should be experimentally determined.
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein G purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Caspase-8
Caspase 8 is expressed as an inactive proenzyme which then undergos proteolytic processing by upstream caspases, to form an active (cleaved) caspase 8 form.
Caspase 8 antibodies are important tools for apoptosis studies and research on the caspase family mediated apoptosis signaling pathway.
Alternate Names
CASP8, Caspase8, Mch5
Gene Symbol
CASP8
Additional Caspase-8 Products
Product Documents for Caspase-8 Antibody (1G12) [Janelia Fluor® 646]
Product Specific Notices for Caspase-8 Antibody (1G12) [Janelia Fluor® 646]
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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