CD11a/CD18 Antibody (hu1124 (Efalizumab)) [Janelia Fluor® 646] - Chimeric

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-52686JF646

Recombinant Monoclonal Antibody.
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Block/Neutralize, CyTOF-ready, Flow Cytometry, Immunohistochemistry

Label

Janelia Fluor 646

Antibody Source

Recombinant Monoclonal Rabbit IgG Kappa Clone # hu1124 (Efalizumab)

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CD11a/CD18 Antibodies »

Product Specifications

Immunogen

Efalizumab binds to CD11a, a subunit of leukocyte function antigen-1 (LFA-1), which is expressed on all leukocytes.

Reactivity Notes

Human

Specificity

Binds to human LFA-1.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Applications

Application
Recommended Usage

Block/Neutralize

Optimal dilutions of this antibody should be experimentally determined.

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CD11a/CD18

The CD11/18 complex of glycoproteins are dimers comprised of a common beta chain and individual alpha chains (CD11a/18 or CD11b/18 and CD11c/18). CD11a/18 is a receptor for C3bi, a complement component, CD11b/18 is Lymphocyte Function Activator, and CDD11c/18 is a lectin-like glycoprotein thought to be important for mediation of cells to other surfaces.

Alternate Names

CD11 antigen-like family member A, CD11a antigen, CD11Aantigen CD11A (p180), lymphocyte function-associated antigen 1, alphapolypeptide, integrin alpha-L, integrin gene promoter, integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen1; alpha polypeptide), Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte function-associated molecule 1 alpha chain, LFA-1, LFA-1 alpha, LFA1A, LFA-1A, lymphocyte function-associated antigen 1

Gene Symbol

ITGAL

Additional CD11a/CD18 Products

Product Documents

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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