Recognizes the human CD24 cell surface antigen, a heavily glycosylated molecule of 35-45kD. CD24 is expressed by granulocytes and B lymphocytes, and by some activated T cells and T cell malignancies.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Scientific Data Images for CD24 Antibody (SN3) - Low Endotoxin

Flow Cytometry: CD24 Antibody (SN3) - Low Endotoxin [NBP2-67237]

Flow Cytometry: CD24 Antibody (SN3) - Low Endotoxin [NBP2-67237] - Staining of human peripheral blood granulocytes with MOUSE ANTI HUMAN CD24: RPE.

Applications for CD24 Antibody (SN3) - Low Endotoxin

Application

Recommended Usage

Flow Cytometry

1:10 - 1:1000

Immunohistochemistry

1:10 - 1:500

Immunohistochemistry-Frozen

1:10 - 1:500

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

Low Endotoxin

Preservative

No Preservative

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CD24

CD24 (also known as heat stable antigen) is a phosphatidylinositol linked cell surface glycoprotein with a polypeptide core of 30 amino acids and high carbohydrate content. The apparent molecular mass of the two forms of CD24 purified from a mouse lymphoma cell line appear to be in the range of 40-60 and 23-30 kDa. CD24 is expressed at all stages of B cell development and on most thymocytes. The absence of expression from mature T cells is closely associated with their maturation from CD4+ CD8+ CD24+ thymocytes to either CD4+ CD8- CD24- or CD4- CD8+ CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. Its ligand is P selectin (CD62P). CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes. CD24 is also a positive marker of pancreatic cancer.

Alternate Names

CD24, CD24A

Gene Symbol

CD24

UniProt

P25063

Additional CD24 Products

Product Documents for CD24 Antibody (SN3) - Low Endotoxin

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for CD24 Antibody (SN3) - Low Endotoxin

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

CD24 Antibody (SN3) - Low Endotoxin

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-67237

Key Product Details

Species Reactivity

Validated:

Applications

Label

Antibody Source

Format

Concentration

View all CD24 Antibodies »

Product Summary for CD24 Antibody (SN3) - Low Endotoxin

Immunogen

Reactivity Notes

Specificity

Clonality

Host

Isotype

Scientific Data Images for CD24 Antibody (SN3) - Low Endotoxin

Flow Cytometry: CD24 Antibody (SN3) - Low Endotoxin [NBP2-67237]

Applications for CD24 Antibody (SN3) - Low Endotoxin

Flow Cytometry

Immunohistochemistry

Immunohistochemistry-Frozen

Formulation, Preparation, and Storage

Purification

Formulation

Format

Preservative

Concentration

Shipping

Stability & Storage

Background: CD24

Alternate Names

Gene Symbol

UniProt

Additional CD24 Products

Product Documents for CD24 Antibody (SN3) - Low Endotoxin

Product Datasheets

COA

Certificate of Analysis

SDS

Product Specific Notices for CD24 Antibody (SN3) - Low Endotoxin