CD25/IL-2R alpha Antibody (Basiliximab) [mFluor Violet 610 SE]
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-52661MFV610
Recombinant Monoclonal Antibody.
![CD25/IL-2R alpha Antibody (Basiliximab) [mFluor Violet 610 SE]](https://resources.bio-techne.com/images/products/nbp2-52661mfv610_rabbit-cd25-il-2r-alpha-mab-basiliximab-mfv610-se-672023915413.png "CD25/IL-2R alpha Antibody (Basiliximab) [mFluor Violet 610 SE] [NBP2-52661MFV610] -")
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Human, Cynomolgus Monkey, Rhesus Macaque
Applications
Block/Neutralize, CyTOF-ready, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot
Label
mFluor Violet 610 SE (Excitation = 421 nm, Emission = 613 nm)
Antibody Source
Recombinant Monoclonal Rabbit IgG Kappa Clone # Basiliximab
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Basiliximab was prepared by immunizing BALB/c mice with CTC 16 cells.
Specificity
Basiliximab recognises the human IL-2R and binds to the epitope (116)ERIYHFV(122) within the extracellular domain of the CD25 subunit -binding is abolished when 2 or more residues within the epitope are mutated. This epitope overlaps with the interaction site of CD25 and IL-2. CD25 is found in the high-affinity IL-2R ((alpha)(beta)(gamma)c) -T cells only express CD25 upon activation. IL-2 binding to IL-2R on T cells modulates proliferation and differentiation.
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG Kappa
Scientific Data Images for CD25/IL-2R alpha Antibody (Basiliximab) [mFluor Violet 610 SE]
CD25/IL-2R alpha Antibody (Basiliximab) [mFluor Violet 610 SE] [NBP2-52661MFV610] -
CD25/IL-2R alpha Antibody (Basiliximab) [mFluor Violet 610 SE] [NBP2-52661MFV610] - Vial of mFluor Violet 610 conjugated antibody. mFluor Violet 610 is optimally excited at 421 nm by the Violet laser (405 nm) and has an emission maximum of 613 nm.Applications for CD25/IL-2R alpha Antibody (Basiliximab) [mFluor Violet 610 SE]
Application
Recommended Usage
Block/Neutralize
Optimal dilutions of this antibody should be experimentally determined.
CyTOF-ready
Optimal dilutions of this antibody should be experimentally determined.
Flow Cytometry
Optimal dilutions of this antibody should be experimentally determined.
Immunocytochemistry/ Immunofluorescence
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry
Optimal dilutions of this antibody should be experimentally determined.
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: CD25/IL-2R alpha
Long Name
Interleukin 2 Receptor alpha
Alternate Names
CD25, IL-2 R alpha, IL-2Ra, IL2R alpha, IL2RA
Gene Symbol
IL2RA
Additional CD25/IL-2R alpha Products
Product Documents for CD25/IL-2R alpha Antibody (Basiliximab) [mFluor Violet 610 SE]
Product Specific Notices for CD25/IL-2R alpha Antibody (Basiliximab) [mFluor Violet 610 SE]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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