CD94 Antibody (18D3) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-28119

Novus Biologicals, part of Bio-Techne
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NBP1-28119
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Key Product Details

Species Reactivity

Validated:

Mouse

Applications

Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2a Kappa Clone # 18D3

Format

Azide and BSA Free

Concentration

0.5 mg/ml

View all CD94 Antibodies »

Product Summary for CD94 Antibody (18D3) - Azide and BSA Free

Immunogen

CHO cells transfected with the B6 allele of CD94

Reactivity Notes

Mouse.

Specificity

Mouse CD94 receptor subunit, Mr 70 kDa

Clonality

Monoclonal

Host

Rat

Isotype

IgG2a Kappa

Scientific Data Images for CD94 Antibody (18D3) - Azide and BSA Free

Flow Cytometry: CD94 Antibody (18D3) - Azide and BSA Free [NBP1-28119]

Flow Cytometry: CD94 Antibody (18D3) - Azide and BSA Free [NBP1-28119]

Flow Cytometry: CD94 Antibody (18D3) [NBP1-28119] - C57BL/6 mouse splenocytes were stained with Rat Anti-Mouse CD94-BIOT (SB Cat. 1809-08) and Mouse Anti-Mouse NK1.1-PE (SB Cat. No. 1805-09) followed by Streptavidin-FITC (SB Cat. No. 7100-02).

Applications for CD94 Antibody (18D3) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

1 ug/10^6 cells
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

0.1M BBS (pH 8.2)

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: CD94

The monoclonal antibody 18D3 reacts with the mouse CD94 receptor subunit, a 70kDa type II transmembrane glycoprotein. CD94 is expressed on the surface of NK cells, NK T cells and some memory phenotype CD8+ cells. (2) When CD94 is paired with NKG2A, C, or E subunit, it binds the nonclassical MHC class Ib molecule Qa-1b and results in a CD94 high population by flow cytometry. (1, 2) Approximately half of NK cells do not express NKG2A, C or E; these cells express CD94 on the surface in a form that does not bind Qa-1b and is believed to be nonfunctional, producing a CD94 low population by flow cytometry. (1, 2) CD94 is thought to play a role in the adhesion and activation of the NK cell lineage.

Alternate Names

CD94, KLRD1

Gene Symbol

KLRD1

Additional CD94 Products

Product Documents for CD94 Antibody (18D3) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for CD94 Antibody (18D3) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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