CD94 Antibody (18d3) [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-28121

Novus Biologicals, part of Bio-Techne
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NBP1-28121
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NBP1-28120
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Key Product Details

Species Reactivity

Validated:

Mouse

Applications

Flow Cytometry

Label

Biotin

Antibody Source

Monoclonal Rat IgG2a Kappa Clone # 18d3

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

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Product Summary for CD94 Antibody (18d3) [Biotin]

Immunogen

CHO cells transfected with the B6 allele of CD94

Reactivity Notes

Mouse.

Specificity

Mouse CD94 receptor subunit, Mr 70 kDa

Clonality

Monoclonal

Host

Rat

Isotype

IgG2a Kappa

Applications for CD94 Antibody (18d3) [Biotin]

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: CD94

The monoclonal antibody 18D3 reacts with the mouse CD94 receptor subunit, a 70kDa type II transmembrane glycoprotein. CD94 is expressed on the surface of NK cells, NK T cells and some memory phenotype CD8+ cells. (2) When CD94 is paired with NKG2A, C, or E subunit, it binds the nonclassical MHC class Ib molecule Qa-1b and results in a CD94 high population by flow cytometry. (1, 2) Approximately half of NK cells do not express NKG2A, C or E; these cells express CD94 on the surface in a form that does not bind Qa-1b and is believed to be nonfunctional, producing a CD94 low population by flow cytometry. (1, 2) CD94 is thought to play a role in the adhesion and activation of the NK cell lineage.

Alternate Names

CD94, KLRD1

Gene Symbol

KLRD1

Additional CD94 Products

Product Documents for CD94 Antibody (18d3) [Biotin]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CD94 Antibody (18d3) [Biotin]

Protect conjugated forms from light.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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