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cIAP-2/HIAP-1 Antibody (OTI1A9)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-46576

Novus Biologicals, part of Bio-Techne
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NBP2-46576

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI1A9

Concentration

1 mg/ml

Product Specifications

Immunogen

Human recombinant protein fragment corresponding to amino acids 255-529 of human BIRC3 (NP_001156) produced in E.coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

68.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for cIAP-2/HIAP-1 Antibody (OTI1A9)

Western Blot: cIAP-2/HIAP-1 Antibody (OTI1A9) [NBP2-46576]

Western Blot: cIAP-2/HIAP-1 Antibody (OTI1A9) [NBP2-46576]

Western Blot: cIAP-2/HIAP-1 Antibody (OTI1A9) [NBP2-46576] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BIRC3 cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BIRC3.
Flow Cytometry: cIAP-2/HIAP-1 Antibody (OTI1A9) [NBP2-46576]

Flow Cytometry: cIAP-2/HIAP-1 Antibody (OTI1A9) [NBP2-46576]

Flow Cytometry: cIAP-2/HIAP-1 Antibody (OTI1A9) [NBP2-46576] - Analysis of HEK293T cells transfected with either overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by BIRC3 antibody.

Applications for cIAP-2/HIAP-1 Antibody (OTI1A9)

Application
Recommended Usage

Flow Cytometry

1:100

Western Blot

1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: cIAP-2/HIAP-1

cIAP2 (baculoviral IAP repeat containing 3) belongs to the IAP family which are suppressors of apoptosis. cIAP2 has a variety of functions including regulation of caspases, modulating inflammatory immunity and signaling and cell proliferation. This protein is known to have interactions with TRAF2, DIABLO, RIPK1, RIPK2 and CASP3. cIAP2 has been studied in relation to lymphoma, leukemia, and several forms of cancer.

Alternate Names

BIRC3, cIAP2, HIAP-1, MIHC

Gene Symbol

BIRC3

Additional cIAP-2/HIAP-1 Products

Product Documents for cIAP-2/HIAP-1 Antibody (OTI1A9)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for cIAP-2/HIAP-1 Antibody (OTI1A9)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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