Dectin-1/CLEC7A Antibody (BD6)
Novus Biologicals, part of Bio-Techne | Catalog # NBP1-21513
![Flow Cytometry: Dectin-1/CLEC7A Antibody (BD6) - BSA Free [NBP1-21513]](https://resources.bio-techne.com/images/products/Dectin-1-CLEC7A-Antibody-BD6-Flow-Cytometry-NBP1-21513-img0002.jpg "Flow Cytometry: Dectin-1/CLEC7A Antibody (BD6) - BSA Free [NBP1-21513]")
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Flow Cytometry
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG2B Clone # BD6
Concentration
1.0 mg/ml
Product Specifications
Immunogen
NIH3T3 cells expressing full length Beta-glucan receptor
Specificity
NBP1-21513 recognizes human Dectin-1, also known as beta-glucan receptor (betaGR), a C-type lectin domain family member. It is a major pathogen pattern-recognition receptor that binds beta-glucans, glucose polymers that form cell-wall components or exopolymers of yeasts, fungi and some bacteria. Beta-glucans have also been used experimentally and therapeutically as immunomodulators that enhance resistance to bacterial, yeast, viral and protozoan infections, as well as tumor formation. Dectin-1 also acts as a co-stimulatory molecule on T-cells to induce their proliferation and is necessary for the TLR2-mediated inflammatory response. It is highly expressed on peripheral blood leukocytes and dendritic cells. Human Dectin-1 has two major (betaGR-A and betaGR-B) and several minor isoforms. betaGR-A and betaGR-B differs by the presence and absence, respectively, of a stalk region. Clone BD6 recognizes betaGR-A only.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2B
Scientific Data Images for Dectin-1/CLEC7A Antibody (BD6)
Flow Cytometry: Dectin-1/CLEC7A Antibody (BD6) - BSA Free [NBP1-21513]
Flow Cytometry: Dectin-1/CLEC7A Antibody (BD6) [NBP1-21513] - Analysis using the FITC conjugate of NBP1-21513. Staining of human peripheral blood monocytes.Applications for Dectin-1/CLEC7A Antibody (BD6)
Application
Recommended Usage
Flow Cytometry
1:25 - 1:200
Formulation, Preparation, and Storage
Purification
Protein G purified
Formulation
PBS
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: Dectin-1/CLEC7A
Additional Dectin-1/CLEC7A Products
Product Documents for Dectin-1/CLEC7A Antibody (BD6)
Product Specific Notices for Dectin-1/CLEC7A Antibody (BD6)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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