Key Product Details

Species Reactivity

Human, Mouse, Zebrafish

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 102B1259.2

Format

Azide and BSA Free

Concentration

0.5 mg/ml

View all Dnmt2 Antibodies »

Product Specifications

Immunogen

This antibody was raised against synthetic peptides corresponding to mouse Dnmt2.

Reactivity Notes

Zebrafish reactivity reported in scientific literature (PMID: 17289917).

Localization

Nuclear

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for Dnmt2 Antibody (102B1259.2) - Azide and BSA Free

Western Blot: Dnmt2 Antibody (102B1259.2)Azide and BSA Free [NBP2-80698]

Western Blot: Dnmt2 Antibody (102B1259.2)Azide and BSA Free [NBP2-80698]

Western Blot: Dnmt2 Antibody (102B1259.2) - Azide and BSA Free [NBP2-80698] - Analysis of Dnmt2 in transfected cell lysate using Dnmt2 monoclonal antibody at 2 ug/ml. Image from the standard format of this antibody.

Applications for Dnmt2 Antibody (102B1259.2) - Azide and BSA Free

Application
Recommended Usage

Western Blot

1:100-1:2000

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS and 0.2% Gelatin

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Dnmt2

Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting and is essential for mammalian development. Dnmt2 is expressed at low levels in adult tissues and its inactivation does not affect DNA methylation or maintenance of methylation. Dnmt2 contains all the sequence motifs diagnostic of DNA (cytosine-5)-methyltransferases but appears to lack the large N-terminal regulatory domain common to other eukaryotic methyltransferases.

Alternate Names

DMNT2, DNA (cytosine-5-)-methyltransferase 2, DNA (cytosine-5)-methyltransferase-like protein 2, DNA methyltransferase homolog HsaIIP, DNA methyltransferase-2, DNA MTase homolog HsaIIP, DNMT2, EC 2.1.1, EC 2.1.1.29, M.HsaIIP, MHSAIIP, PUMET, RNMT1, tRNA (cytosine-5-)-methyltransferase, tRNA aspartic acid methyltransferase 1

Gene Symbol

TRDMT1

Additional Dnmt2 Products

Product Documents for Dnmt2 Antibody (102B1259.2) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Dnmt2 Antibody (102B1259.2) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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