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Drebrin 1 Antibody (DBN-N-03)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-22344

Novus Biologicals, part of Bio-Techne
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NBP2-22344
Conjugate
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Key Product Details

Species Reactivity

Validated:

Human

Applications

CyTOF-ready, Flow (Intracellular), Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # DBN-N-03

Concentration

1.0 mg/ml

Product Summary for Drebrin 1 Antibody (DBN-N-03)

Immunogen

Bacterially expressed N-terminal fragment of recombinant human Drebrin Antibody (DBN-N-03)

Specificity

The mouse monoclonal Drebrin Antibody (DBN-N-03) recognizes drebrin, an approximately 100-125 kDa regulator of actin cytoskeleton.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Theoretical MW

125 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Drebrin 1 Antibody (DBN-N-03)

Western Blot: Drebrin 1 Antibody (DBN-N-03) [NBP2-22344]

Western Blot: Drebrin 1 Antibody (DBN-N-03) [NBP2-22344]

Western Blot: Drebrin 1 Antibody (DBN-N-03) [NBP2-22344] - Drebrin Antibody (DBN-N-03) Western blotting analysis of drebrin expression in REH, Ramos, and Nalm-6 cell lysate using mouse monoclonal antibody.
Flow Cytometry: Drebrin 1 Antibody (DBN-N-03) [NBP2-22344]

Flow Cytometry: Drebrin 1 Antibody (DBN-N-03) [NBP2-22344]

Flow Cytometry: Drebrin 1 Antibody (DBN-N-03) [NBP2-22344] - Surface staining (mass cytometry) of brain tumor cells with anti-drebrin 152Sm. Gated on singlets.

Applications for Drebrin 1 Antibody (DBN-N-03)

Application
Recommended Usage

Flow (Intracellular)

1-4 ug/ml

Flow Cytometry

1-4 ug/ml
Application Notes
This antibody is Cytof ready.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

TBS (pH 8.0)

Preservative

0.9% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Drebrin 1

Drebrins are actin-binding proteins, that are developmentally regulated in the process of neuronal growth. Three isoforms, E1 and E2 (embryonic) and A (adult) are generated by alternative RNA splicing from a single debrin gene in the chicken brain. The expression pattern of each isoform is regulated spatially and temporally in the developing brain. It has been suggested that debrin is one of the intracellular regulators of the neuronal morphogenesis (4). Debrin has also been detected in other kinds of non-neuronal human and bovine tissue but its exact role is unknown.

Alternate Names

D0S117E, DBN1, Drba, Drebrin A, Drebrin E, Drebrin E2

Gene Symbol

DBN1

Additional Drebrin 1 Products

Product Documents for Drebrin 1 Antibody (DBN-N-03)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Drebrin 1 Antibody (DBN-N-03)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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