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Drebrin 1 Antibody (DBN-N-03) [PE/Cy7]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-22344PECY7

Novus Biologicals, part of Bio-Techne
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NBP2-22344PECY7
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry

Label

PE/Cy7 (Excitation = 488 nm, Emission = 778 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # DBN-N-03

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for Drebrin 1 Antibody (DBN-N-03) [PE/Cy7]

Immunogen

Bacterially expressed N-terminal fragment of recombinant human Drebrin Antibody (DBN-N-03)

Specificity

The mouse monoclonal Drebrin Antibody (DBN-N-03) recognizes drebrin, an approximately 100-125 kDa regulator of actin cytoskeleton.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for Drebrin 1 Antibody (DBN-N-03) [PE/Cy7]

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: Drebrin 1

Drebrins are actin-binding proteins, that are developmentally regulated in the process of neuronal growth. Three isoforms, E1 and E2 (embryonic) and A (adult) are generated by alternative RNA splicing from a single debrin gene in the chicken brain. The expression pattern of each isoform is regulated spatially and temporally in the developing brain. It has been suggested that debrin is one of the intracellular regulators of the neuronal morphogenesis (4). Debrin has also been detected in other kinds of non-neuronal human and bovine tissue but its exact role is unknown.

Alternate Names

D0S117E, DBN1, Drba, Drebrin A, Drebrin E, Drebrin E2

Gene Symbol

DBN1

Additional Drebrin 1 Products

Product Documents for Drebrin 1 Antibody (DBN-N-03) [PE/Cy7]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Drebrin 1 Antibody (DBN-N-03) [PE/Cy7]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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