ENPP-1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-27561

Novus Biologicals, part of Bio-Techne
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NBP2-27561
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Key Product Details

Species Reactivity

Validated:

Human, Rat, Chicken

Cited:

Human, Rat, Avian - Chicken

Predicted:

Mouse (100%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA, Western Blot

Cited:

Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all ENPP-1 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-KTHLPTFSQED corresponding to C-Terminus according to NP_006199.2.

Reactivity Notes

Rat reactivity reported in (PMID: 17569759). Chicken reactivity reported in scientific literature (PMID: 30271993).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for ENPP-1 Antibody

ENPP-1 Antibody

Immunohistochemistry-Paraffin: ENPP-1 Antibody [NBP2-27561] -

Immunohistochemistry-Paraffin: ENPP-1 Antibody [NBP2-27561] - (4ug/ml) staining of paraffin embedded Human Thyroid Gland. Heat induced antigen retrieval with citrate buffer Ph 6, HRP-staining.
ENPP-1 Antibody

Immunohistochemistry-Paraffin: ENPP-1 Antibody [NBP2-27561] -

Immunohistochemistry-Paraffin: ENPP-1 Antibody [NBP2-27561] - Negative Control showing staining of paraffin embedded Human Thyroid Gland, with no primary antibody.

Applications for ENPP-1 Antibody

Application
Recommended Usage

Immunohistochemistry

4 ug/ml

Immunohistochemistry-Paraffin

4 ug/ml

Peptide ELISA

1:64000
Application Notes
WB reactivity reported in scientific literature (PMID: 20634316).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: ENPP-1

ENPP1 has a broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. It can hydrolyze nucleoside 5' triphosphates such as ATP, GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate. It can also hydrolyze diadenosine polyphosphates and 3',5'-cAMP to AMP. It may play a role in the regulation of pyrophosphate production, the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling.

Long Name

Ectonucleotide Pyrophosphatase/Phosphodiesterase 1

Alternate Names

ENPP1, Ly-41 Antigen, M6S1, NPP1, NPPS, PCA1, PDNP1

Gene Symbol

ENPP1

UniProt

NP_006199

Additional ENPP-1 Products

Product Documents for ENPP-1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for ENPP-1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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