Key Product Details

Species Reactivity

Validated:

Zebrafish

Applications

ELISA, Immunohistochemistry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # V8P1G5*F2

Format

BSA Free

Concentration

1 mg/ml

View all FGF acidic/FGF1 Antibodies »

Product Summary for FGF acidic/FGF1 Antibody (V8P1G5*F2) - BSA Free

Immunogen

Ovalbumin-conjugated synthetic peptide LPRQVEQEED (C-terminal sequence)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

The clone number is listed as V8P1G5*F2 in the scientific literature.

Scientific Data Images for FGF acidic/FGF1 Antibody (V8P1G5*F2) - BSA Free

Immunohistochemistry: FGF acidic/FGF1 Antibody (V8P1G5*F2) - BSA Free [NBP2-50406]

Immunohistochemistry: FGF acidic/FGF1 Antibody (V8P1G5*F2) - BSA Free [NBP2-50406]

Immunohistochemistry: FGF acidic/FGF1 Antibody (V8P1G5F2) [NBP2-50406] - Whole-mount zebrafish embryo

Applications for FGF acidic/FGF1 Antibody (V8P1G5*F2) - BSA Free

Application
Recommended Usage

ELISA

1:100 - 1:2000

Immunohistochemistry

1:10 - 1:500
Application Notes
Positive control(s): ELISA - peptide immunogen; IHC - zebrafish embryo.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: FGF acidic/FGF1

FGF acidic, also known as FGF-1, ECGF, and HBGF-1, is a secreted mitogen that stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. It plays a number of roles in development, regeneration, and angiogenesis. FGF acidic is released extracellularly as a disulfide-linked homodimer and is stored in complex with extracellular heparan sulfate. The association of FGF acidic with heparan sulfate is a prerequisite for its subsequent interaction with FGF receptors. Internalized FGF acidic can translocate to the cytosol and to the nucleus. Intracellular FGF acidic functions as a survival factor by inhibiting p53 activity and proapoptotic signaling.

Long Name

Fibroblast Growth Factor acidic

Alternate Names

alpha-ECGF, beta-ECGF, FGF acidic, FGF-1, HBGF-1

Gene Symbol

FGF1

Additional FGF acidic/FGF1 Products

Product Documents for FGF acidic/FGF1 Antibody (V8P1G5*F2) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for FGF acidic/FGF1 Antibody (V8P1G5*F2) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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