FGF acidic/FGF1 Products
FGF acidic/FGF1, also known as ECGF and HBGF-1, is a secreted mitogen that stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. It plays a number of roles in development, regeneration, and angiogenesis.
FGF1 is released extracellularly as a disulfide-linked homodimer and is stored in complex with extracellular heparan sulfate. The association of FGF1 with heparan sulfate is a prerequisite for its subsequent interaction with FGF receptors. Internalized FGF1 can translocate to the cytosol and to the nucleus. Intracellular FGF1 functions as a survival factor by inhibiting p53 activity and proapoptotic signaling.
Products:
80 results for "FGF acidic/FGF1" in Products
80 results for "FGF acidic/FGF1" in Products
FGF acidic/FGF1 Products
FGF acidic/FGF1, also known as ECGF and HBGF-1, is a secreted mitogen that stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. It plays a number of roles in development, regeneration, and angiogenesis.
FGF1 is released extracellularly as a disulfide-linked homodimer and is stored in complex with extracellular heparan sulfate. The association of FGF1 with heparan sulfate is a prerequisite for its subsequent interaction with FGF receptors. Internalized FGF1 can translocate to the cytosol and to the nucleus. Intracellular FGF1 functions as a survival factor by inhibiting p53 activity and proapoptotic signaling.
Products:
| Source: | E. coli |
| Accession #: | NP_000791 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | P05230.1 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, IHC, Neut |
| Sensitivity: | 13.9 pg/mL |
| Applications: | ELISA |
| Assay Range: | 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
| Source: | E. coli |
| Accession #: | NP_034327 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | NP_000791 |
| Applications: | BA |
| Reactivity: | Human, Plant |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2E12 |
| Applications: | IHC, WB, ELISA, ICC/IF, IP |
![Western Blot: FGF acidic/FGF1 Antibody (2E12) [H00002246-M02]](https://resources.bio-techne.com/images/products/FGF-acidic-FGF1-Antibody-2E12-Western-Blot-H00002246-M02-img0011.jpg "Western Blot: FGF acidic/FGF1 Antibody (2E12) [H00002246-M02]")
| Reactivity: | Mouse |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, Neut |
| Assay Range: | 12.5 - 800 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #3117 |
| Applications: | WB |
| Reactivity: | Bovine |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, Neut |
| Source: | Bovine Brain |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #939902 |
| Applications: | WB, IHC |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #3X3E5 |
| Applications: | WB, ICC/IF |
![Western Blot: FGF acidic/FGF1 Antibody (3X3E5) [NBP3-16609]](https://resources.bio-techne.com/images/products/FGF-acidic-FGF1-Antibody-3X3E5-Western-Blot-NBP3-16609-img0004.jpg "Western Blot: FGF acidic/FGF1 Antibody (3X3E5) [NBP3-16609]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4D2 |
| Applications: | WB, ICC/IF |
![Western Blot: FGF acidic/FGF1 Antibody (OTI4D2) [NBP1-47748]](https://resources.bio-techne.com/images/products/FGF-acidic-FGF1-Antibody-4D2-Western-Blot-NBP1-47748-img0006.jpg "Western Blot: FGF acidic/FGF1 Antibody (OTI4D2) [NBP1-47748]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #S05-6A4 |
| Applications: | WB |
![Western Blot: FGF acidic/FGF1 Antibody (S05-6A4) [NBP3-19634]](https://resources.bio-techne.com/images/products/FGF-acidic-FGF1-Antibody-S05-6A4-Western-Blot-NBP3-19634-img0001.jpg "Western Blot: FGF acidic/FGF1 Antibody (S05-6A4) [NBP3-19634]")
| Reactivity: | Human, Mouse, Rat, Porcine |
| Details: | Mouse IgG1 kappa Monoclonal Clone #C16 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Porcine |
| Details: | Mouse IgG1 kappa Monoclonal Clone #C14 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Zebrafish |
| Details: | Mouse IgG1 kappa Monoclonal Clone #V8P1G5*F2 |
| Applications: | IHC, ELISA |
![Immunohistochemistry: FGF acidic/FGF1 Antibody (V8P1G5*F2) - BSA Free [NBP2-50406]](https://resources.bio-techne.com/images/products/FGF-acidic-FGF1-Antibody-V8P1G5F2-Immunohistochemistry-NBP2-50406-img0001.jpg "Immunohistochemistry: FGF acidic/FGF1 Antibody (V8P1G5*F2) - BSA Free [NBP2-50406]")
| Applications: | WB |
![Western Blot: FGF acidic/FGF1 Overexpression Lysate [NBL1-10687]](https://resources.bio-techne.com/images/products/FGF1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-10687-img0002.jpg "Western Blot: FGF acidic/FGF1 Overexpression Lysate [NBL1-10687]")
| Applications: | WB |
![Western Blot: FGF acidic/FGF1 Overexpression Lysate [NBP2-09719]](https://resources.bio-techne.com/images/products/FGF1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-09719-img0001.jpg "Western Blot: FGF acidic/FGF1 Overexpression Lysate [NBP2-09719]")
| Applications: | WB |
![Western Blot: FGF acidic/FGF1 Overexpression Lysate [NBP2-09718]](https://resources.bio-techne.com/images/products/FGF1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-09718-img0001.jpg "Western Blot: FGF acidic/FGF1 Overexpression Lysate [NBP2-09718]")
| Applications: | WB |
![Western Blot: FGF acidic/FGF1 Overexpression Lysate [NBP2-09715]](https://resources.bio-techne.com/images/products/FGF1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-09715-img0001.jpg "Western Blot: FGF acidic/FGF1 Overexpression Lysate [NBP2-09715]")