FGF acidic/FGF1 Products
FGF acidic/FGF1, also known as ECGF and HBGF-1, is a secreted mitogen that stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. It plays a number of roles in development, regeneration, and angiogenesis.
FGF1 is released extracellularly as a disulfide-linked homodimer and is stored in complex with extracellular heparan sulfate. The association of FGF1 with heparan sulfate is a prerequisite for its subsequent interaction with FGF receptors. Internalized FGF1 can translocate to the cytosol and to the nucleus. Intracellular FGF1 functions as a survival factor by inhibiting p53 activity and proapoptotic signaling.
Products:
70 results for "FGF acidic/FGF1" in Products
70 results for "FGF acidic/FGF1" in Products
FGF acidic/FGF1 Products
FGF acidic/FGF1, also known as ECGF and HBGF-1, is a secreted mitogen that stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. It plays a number of roles in development, regeneration, and angiogenesis.
FGF1 is released extracellularly as a disulfide-linked homodimer and is stored in complex with extracellular heparan sulfate. The association of FGF1 with heparan sulfate is a prerequisite for its subsequent interaction with FGF receptors. Internalized FGF1 can translocate to the cytosol and to the nucleus. Intracellular FGF1 functions as a survival factor by inhibiting p53 activity and proapoptotic signaling.
Products:
Source: | E. coli |
Accession #: | NP_000791 |
Applications: | BA |
Source: | E. coli |
Accession #: | NP_034327 |
Applications: | BA |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB, Simple Western, IHC, Neut |
Sensitivity: | 13.9 pg/mL |
Applications: | ELISA |
Assay Range: | 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
Source: | E. coli |
Accession #: | P05230.1 |
Applications: | BA |
Reactivity: | Human, Plant |
Details: | Mouse IgG1 kappa Monoclonal Clone #2E12 |
Applications: | IHC, WB, ELISA, ICC/IF, IP |
Reactivity: | Mouse |
Details: | Sheep IgG Polyclonal |
Applications: | WB, Neut |
Source: | E. coli |
Accession #: | NP_000791 |
Applications: | BA |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #3117 |
Applications: | WB |
Reactivity: | Bovine |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, Neut |
Source: | Bovine Brain |
Applications: | BA |
Assay Range: | 12.5 - 800 pg/mL |
Applications: | ELISA |
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #939902 |
Applications: | WB, IHC |
Applications: | ELISA |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #3X3E5 |
Applications: | WB, ICC/IF |
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 Monoclonal Clone #OTI4D2 |
Applications: | WB, ICC/IF |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #S05-6A4 |
Applications: | WB |
Reactivity: | Human, Mouse, Rat, Porcine |
Details: | Mouse IgG1 kappa Monoclonal Clone #C16 |
Applications: | IHC, WB, ICC/IF |
Reactivity: | Zebrafish |
Details: | Mouse IgG1 kappa Monoclonal Clone #V8P1G5*F2 |
Applications: | IHC, ELISA |
Reactivity: | Human, Porcine |
Details: | Mouse IgG1 kappa Monoclonal Clone #C14 |
Applications: | IHC, WB, ICC/IF |
Applications: | WB |
Applications: | WB |
Applications: | WB |
Applications: | WB |