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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Chicken (95%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

Antibody was raised against a 19 amino acid peptide near the carboxy terminus of human FGFR3. The immunogen is located within amino acids 630 - 680 of FGFR3. Amino Acid Squence: RDVHNLDYYKKTTNGRLPV

Specificity

At least three isoforms of FGFR3 are known to exist; this antibody will detect all three.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

92, 98 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for FGFR3 Antibody - BSA Free

Western Blot: FGFR3 AntibodyBSA Free [NBP2-41227]

Western Blot: FGFR3 AntibodyBSA Free [NBP2-41227]

Western Blot: FGFR3 Antibody [NBP2-41227] - SK-N-SH cell lysate with FGFR3 antibody at (A) 0.5 and (B) 1 ug/mL.
Immunocytochemistry/ Immunofluorescence: FGFR3 Antibody - BSA Free [NBP2-41227]

Immunocytochemistry/ Immunofluorescence: FGFR3 Antibody - BSA Free [NBP2-41227]

Immunocytochemistry/Immunofluorescence: FGFR3 Antibody [NBP2-41227] - Immunofluorescence of FGFR3 in rat brain tissue with FGFR3 antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: FGFR3 Antibody - BSA Free [NBP2-41227]

Immunohistochemistry-Paraffin: FGFR3 Antibody - BSA Free [NBP2-41227]

Immunohistochemistry-Paraffin: FGFR3 Antibody [NBP2-41227] - Rat brain tissue with FGFR3 antibody at 2.5 ug/mL.

Applications for FGFR3 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Western Blot

1 - 2 ug/mL

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: FGFR3

FGF activity is mediated by a family of type I transmembrane tyrosine kinases, which undergo dimerization and autophosphorylation after ligand binding. Five distinct genes encode closely related FGF receptors, FGF R1 through 5. FGF Rs contain three Ig-like domains and a stretch of acidic residues between the first and second Ig-like domains. FGF R1, 2, 3, and -4 have a cytoplasmic split tyrosine-kinase domain, but FGF R5 does not. Multiple forms of FGF R1, 2, and 3 are generated by alternative splicing

Long Name

Fibroblast Growth Factor Receptor 3

Alternate Names

CD333, CEK, FGF R3, JTK4

Gene Symbol

FGFR3

Additional FGFR3 Products

Product Documents for FGFR3 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for FGFR3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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