FSH beta Antibody (FSHb/1062)
Novus Biologicals, part of Bio-Techne | Catalog # NBP2-45132
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Validated:
Human
Cited:
Human
Applications
Validated:
Immunohistochemistry, Immunohistochemistry-Paraffin
Cited:
Immunohistochemistry-Paraffin
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 kappa Clone # FSHb/1062
Concentration
0.2 mg/ml
Product Specifications
Immunogen
Recombinant full-length FSH beta sub-unit (Uniprot: P01225)
Localization
Cytoplasmic, secreted
Specificity
This monoclonal antibody reacts with a protein of 22kDa, identified as beta sub-unit of FSH. It does not cross react with the alpha sub-unit. Follicle stimulating hormone (FSH) is a hormone synthesized and secreted by gonadotrophs in the anterior pituitary gland. In the ovary, FSH stimulates the growth of immature Graafian follicles to maturation. As the follicle grows, it releases inhibin, which deactivates the FSH production. In men, FSH enhances the production of androgen-binding protein by the Sertoli cells of the testis and is critical for spermatogenesis. FSH and LH act synergistically in reproduction. FSH is a useful marker in the classification of pituitary tumors and the study of pituitary disease.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1 kappa
Theoretical MW
22 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Description
200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP2-47734)
Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.
Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.
Scientific Data Images for FSH beta Antibody (FSHb/1062)
Immunohistochemistry-Paraffin: FSH beta Antibody (FSHb/1062) [NBP2-45132]
Immunohistochemistry-Paraffin: FSH beta Antibody (FSHb/1062) [NBP2-45132] - Human Pituitary stained with FSH-beta Monoclonal Antibody (FSHb/1062).Applications for FSH beta Antibody (FSHb/1062)
Application
Recommended Usage
Immunohistochemistry-Paraffin
0.1-0.2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 0.1-0.2ug/ml for 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.
Optimal dilution for a specific application should be determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
10 mM PBS with 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.2 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C.
Background: FSH beta
Long Name
Follicle Stimulating Hormone, beta
Alternate Names
Follitropin, FSHB
Gene Symbol
FSHB
UniProt
Additional FSH beta Products
Product Documents for FSH beta Antibody (FSHb/1062)
Product Specific Notices for FSH beta Antibody (FSHb/1062)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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