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GABA-AR alpha 4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-32077

Novus Biologicals, part of Bio-Techne
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NBP2-32077

Key Product Details

Species Reactivity

Human

Applications

Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

Product Specifications

Immunogen

The immunogen this antibody was made to, maps to a region between residue 425 to 475 of human GABA A Receptor alpha 4 Antibody, Alpha 4 using the numbering given in entry NP_000800.2 (GeneID 2557).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for GABA-AR alpha 4 Antibody

Immunoprecipitation: GABA-AR alpha 4 Antibody [NBP2-32077]

Immunoprecipitation: GABA-AR alpha 4 Antibody [NBP2-32077]

Immunoprecipitation: GABA-AR alpha 4 Antibody [NBP2-32077] - Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) prepared using NETN buffer from HeLa cells. Antibodies: Affinity purified rabbit anti- NBP2-32077 used for IP at 6 ug per reaction. was also immunoprecipitated by rabbit anti- BL16428. For blotting immunoprecipitated GABA-A R alpha 4 Antibody, NBP2-32077 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Applications for GABA-AR alpha 4 Antibody

Application
Recommended Usage

Immunoprecipitation

2 - 10 ug/mg lysate

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: GABA-A R alpha 4

GABA (A) receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA (A). Some of these drugs include benzodiazepines, anticonvulsants, and anesthetics. GABA (A) Receptors are comprised of subunits and these are further classified into 3 major groups (alpha, beta, and gamma). The subunits determine the pharmacological characteristics.

Long Name

gamma-Aminobutyric Acid Type A Receptor, alpha-4 Polypeptide

Alternate Names

GABAAR alpha 4, GABAARa4, GABRA4

Gene Symbol

GABRA4

Additional GABA-A R alpha 4 Products

Product Documents for GABA-AR alpha 4 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GABA-AR alpha 4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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