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GDF-15 Antibody (ponsegromab) - Humanized

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-28880

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Functional

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Human IgG1 Clone # ponsegromab

Concentration

LYOPH mg/ml

Product Specifications

Immunogen

GDF15 / MIC1

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Endotoxin Level

< 0.001EU/ug,determined by LAL method.

Description

Expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Also known as 'ponsegromab'.

Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.

Scientific Data Images for GDF-15 Antibody (ponsegromab) - Humanized

GDF-15 Antibody (ponsegromab) - Humanized

ELISA: GDF-15 Antibody (ponsegromab) - Humanized[NBP3-28880] -

Immobilized Mouse GDF15 / MIC-1, His Tag at 2 ug/mL can bind GDF-15 Antibody (ponsegromab) - Humanized, EC50=0.005700 ug/mL
GDF-15 Antibody (ponsegromab) - Humanized

ELISA: GDF-15 Antibody (ponsegromab) - Humanized[NBP3-28880] -

Immobilized Human GDF15 / MIC-1, His Tag at 2 μg/mL can bind GDF-15 Antibody (ponsegromab) - Humanized, EC50=0.004270 ug/mL

Applications for GDF-15 Antibody (ponsegromab) - Humanized

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Formulation

Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: GDF-15

Growth differentiation factor 15 (GDF15) is a transforming growth factor beta superfamily member that acts to regulate inflammatory and apoptotic responses in injured or diseased tissues. GDF15 is most strongly expressed in the liver, placenta and kidney.

GDF15 antibodies are useful for studies on inflamation and immune system research.

Long Name

Growth Differentiation Factor 15

Alternate Names

GDF15, MIC-1, NAG-1, PDF, PLAB, PTGF-beta

Gene Symbol

GDF15

UniProt

Additional GDF-15 Products

Product Documents for GDF-15 Antibody (ponsegromab) - Humanized

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for GDF-15 Antibody (ponsegromab) - Humanized

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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