Glypican 3 Antibody (024)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-23451

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-23451-100ul
NBP3-23451-20ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 024

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Glypican 3 Antibodies »

Product Summary for Glypican 3 Antibody (024)

Immunogen

This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the center region of the Human Glypican 3

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C.

Scientific Data Images for Glypican 3 Antibody (024)

Glypican 3 Antibody (024)

Flow Cytometry: Glypican 3 Antibody (024) [NBP3-23451] -

Flow Cytometry: Glypican 3 Antibody (024) [NBP3-23451] - Flow cytometric analysis of Human Glypican 3 expression on HepG2 cells. Cells were stained with NBP3-23451, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.

Applications for Glypican 3 Antibody (024)

Application
Recommended Usage

Flow Cytometry

1:25-1:100
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Glypican 3

The Glypican 3 (GPC3) gene encodes for a member of the glypican-related integral membrane proteoglycan family (GRIPS). Two isoforms of the protein exist, isoform 1 at a length of 580 amino acids long and 65 kDA while isoform 2 is 526 amino acids long at 59 kDA. The protein encoded by GPC3 is thought to prevent the dipeptidyl peptidase activity of DPP4 and may participate in the suppression and regulation of growth in the predominately mesodermal tissues and organs. The GPC3 gene participates in the Wnt signaling pathway, metabolism, and visual phototransduction through interactions with genes FGF2, WNT3A, WNT7B, BCAN, and BGN. GPC3 has been researched in various diseases such as paine syndrome, horner's sundrome, liver cirrhosis, simpson-golabi-behmel syndrome, germ cell tumors, wilms tumors, complex regional pain syndrome, and hepatocellulcar carcinoma.

Alternate Names

GPC3

Gene Symbol

GPC3

Additional Glypican 3 Products

Product Documents for Glypican 3 Antibody (024)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Glypican 3 Antibody (024)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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