GSK-3 alpha Antibody [PE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-97994PE

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Product Datasheet / COA / SDS

View Available Conjugates

Conjugate

Catalog #

Unconjugated

NBP2-97994

Alexa Fluor 350

NBP2-97994AF350

Alexa Fluor 405

NBP2-97994AF405

Alexa Fluor 488

NBP2-97994AF488

Alexa Fluor 532

NBP2-97994AF532

Alexa Fluor 594

NBP2-97994AF594

Alexa Fluor 647

NBP2-97994AF647

Alexa Fluor 700

NBP2-97994AF700

Alexa Fluor 750

NBP2-97994AF750

Allophycocyanin

NBP2-97994APC

Biotin

NBP2-97994B

CoraFluor 1

NBP2-97994CL1

DyLight 350

NBP2-97994UV

DyLight 405

NBP2-97994V

DyLight 488

NBP2-97994G

DyLight 550

NBP2-97994R

DyLight 594

NBP2-97994DL594

DyLight 650

NBP2-97994C

DyLight 680

NBP2-97994FR

DyLight 755

NBP2-97994IR

FITC

NBP2-97994F

HRP

NBP2-97994H

Janelia Fluor 525

NBP2-97994JF525

Janelia Fluor 549

NBP2-97994JF549

Janelia Fluor 585

NBP2-97994JF585

Janelia Fluor 635

NBP2-97994JF635

Janelia Fluor 646

NBP2-97994JF646

Janelia Fluor 669

NBP2-97994JF669

mFluor Violet 450 SE

NBP2-97994MFV450

mFluor Violet 500 SE

NBP2-97994MFV500

mFluor Violet 610 SE

NBP2-97994MFV610

PerCP

NBP2-97994PCP

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all GSK-3 alpha Antibodies »

Product Summary for GSK-3 alpha Antibody [PE]

Immunogen

Produced in rabbits immunized with E. coli-derived Human GSK-3 alpha fragment.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for GSK-3 alpha Antibody [PE]

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: GSK-3 alpha

Glycogen synthases kinase 3 alpha (GSK3-alpha) is a multifunctional Serine/Threonine protein kinase, one of two isoforms of GSK3 (1). Originally identified as a regulator of glycogen synthase, it has been shown to be involved in the hormonal control of several regulatory factors and transcription factors. GSK3-alpha activity is down regulated by phosphorylation on Serine 21 by PKB, or activated by phosphorylation on Tyrosine 279 (2). Insulin inactivates GSK3-alpha by rapid phosphorylation which leads to activation of Glycogen Synthase in the cells (3). GSK3-alpha activitiy has been linked to a pathogenic mechanism in Alzheimer's disease (4).

Long Name

Glycogen Synthase Kinase 3 alpha

Alternate Names

GSK3 alpha, GSK3A

Gene Symbol

GSK3A

Additional GSK-3 alpha Products

Product Documents for GSK-3 alpha Antibody [PE]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for GSK-3 alpha Antibody [PE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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