Human beta-1 Adrenergic R/ADRB1 Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB10119
Recombinant Monoclonal Antibody.
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Rabbit IgG Clone # 2203D
Product Specifications
Immunogen
Synthetic peptide containing human beta‑1 Adrenergic R/ADRB1
Accession # P08588
Accession # P08588
Specificity
Detects human beta‑1 Adrenergic R/ADRB1 in direct ELISAs.
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG
Scientific Data Images for Human beta-1 Adrenergic R/ADRB1 Antibody
Detection of Human beta‑1 Adrenergic R/ADRB1 by Western Blot.
Western blot shows lysates of human heart ventricle tissue. PVDF membrane was probed with 1 µg/mL of Rabbit Anti-Human beta-1 Adrenergic R/ADRB1 Monoclonal Antibody (Catalog # MAB10119) followed by HRP-conjugated Anti-Rabbit IgG Secondary Antibody (Catalog # HAF008). A specific band was detected for beta-1 Adrenergic R/ADRB1 at approximately 52 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.Applications for Human beta-1 Adrenergic R/ADRB1 Antibody
Application
Recommended Usage
Western Blot
1 µg/mL
Sample: Human heart ventricle tissue
Sample: Human heart ventricle tissue
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: beta-1 Adrenergic R/ADRB1
The beta-1 Adrenergic Receptor (ADRB1) is a 477 aminoacids long and seven-transmembrane domain protein that belongs to the G protein-coupled receptor (GPCR) 1 family. The adrenergic receptors, including ADRB1, are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. ADRB1 binds epinephrine and norepinephrine with approximately equal affinity. ADRB1 is localized at the plasma membrane. It is also found in the Golgi upon Golgi-associated PDZ and coiled-coil motif-containing protein (GOPC) overexpression.
Long Name
Beta-1 Adrenergic Receptor
Alternate Names
ADRB1, ADRB1R, beta-1 AdrenergicR, beta1 AdrenergicR
Gene Symbol
ADRB1
UniProt
Additional beta-1 Adrenergic R/ADRB1 Products
Product Documents for Human beta-1 Adrenergic R/ADRB1 Antibody
Product Specific Notices for Human beta-1 Adrenergic R/ADRB1 Antibody
For research use only
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