Human Claudin-1 APC-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB4618A
Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Human
Cited:
Human
Applications
Validated:
Flow Cytometry
Cited:
Flow Cytometry
Label
Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)
Antibody Source
Monoclonal Rat IgG2A Clone # 421203
Product Specifications
Immunogen
CHO Chinese hamster ovary cell line transfected with human Claudin-1
Met1-Val211
Accession # O95832
Met1-Val211
Accession # O95832
Specificity
Stains human Claudin-1 transfectants but not irrelevant transfectants.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2A
Scientific Data Images for Human Claudin-1 APC-conjugated Antibody
Detection of Claudin-1 in PC-3 Human Cell Line by Flow Cytometry.
PC-3 human prostate cancer cell line was stained with Rat Anti-Human Claudin-1 APC-conjugated Monoclonal Antibody (Catalog # FAB4618A, filled histogram) or isotype control antibody (Catalog # IC006A, open histogram). View our protocol for Staining Membrane-associated Proteins.Applications for Human Claudin-1 APC-conjugated Antibody
Application
Recommended Usage
Flow Cytometry
10 µL/106 cells
Sample: PC‑3 human prostate cancer cell line
Sample: PC‑3 human prostate cancer cell line
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: Claudin-1
Claudin-1 is a 23 kDa multipass membrane protein in the Claudin family of epithelial tight junction proteins. Claudin-1 is expressed by epithelial cells in a wide variety of tissues as well as in Langerhans cells and dendritic cells. It is up or downregulated in many cancers and is required for the entry of hepatitis C virus into hepatocytes. Human Claudin-1 shares 91% aa sequence identity with mouse and rat Claudin-1.
Alternate Names
Claudin1, CLD1, CLDN1, SEMP1
Gene Symbol
CLDN1
UniProt
Additional Claudin-1 Products
Product Documents for Human Claudin-1 APC-conjugated Antibody
Product Specific Notices for Human Claudin-1 APC-conjugated Antibody
For research use only
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