Human Coagulation Factor XIV/Protein C Biotinylated Antibody
R&D Systems, part of Bio-Techne | Catalog # BAF3349
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
Biotin
Antibody Source
Polyclonal Goat IgG
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Coagulation Factor XIV/Protein C
Ala43-Pro461
Accession # P04070
Ala43-Pro461
Accession # P04070
Specificity
Detects human Coagulation Factor XIV/Protein C in Western blots. In Western blots, less than 5% cross-reactivity with recombinant human (rh) Factor VII, rhFactor X, and rhFactor XI is observed.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications
Application
Recommended Usage
Western Blot
0.1 µg/mL
Sample: Recombinant Human Coagulation Factor XIV/Protein C (Catalog # 3349-SE)
Sample: Recombinant Human Coagulation Factor XIV/Protein C (Catalog # 3349-SE)
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Coagulation Factor XIV/Protein C
Coagulation factor XIV, also known as Protein C, has anti-coagulation activity by degrading factors VIIIa and Va, which are required for thrombin activation. Protein C deficiency results in hereditary thrombophilia, and a severe recessive form may result in massive thrombosis fatal to patient. The deduced amino acid sequence of human protein C predicts a signal peptide (aa 1‑32), a propeptide (aa 33‑42), and a mature chain (aa 43‑461), which can be converted into two disulfide-linked chains (light: aa 43‑199 and heavy: aa 200‑461). The amino acid sequence of human protein C is 99.8%, 80%, 70%, 69% and 54% identical to that of chimpanzee, canine, rat, mouse and chicken.
Long Name
Vitamin K-dependent Protein C
Alternate Names
Autoprothrombin IIA, PROC, Protein C
Gene Symbol
PROC
UniProt
Additional Coagulation Factor XIV/Protein C Products
Product Specific Notices
For research use only
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