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Coagulation Factor XIV/Protein C Products

Coagulation Factor XIV / Protein C is a vitamin K-dependent serine protease synthesized in liver as a single-chain precursor. Present in plasma at 3 to 5 mg/L, protein C plays a key role in anticoagulation. Physiologically, the inactive forms of protein C are converted to the active form by thrombin, which releases the activation peptide. The active protein C cleaves factor VIIIa and Va to inactivate them. This anticoagulation activity can be enhanced by a presence of a cofactor such as protein S.

In hereditary thrombophilia, Coagulation Factor XIV /protein C deficiency is caused by a genetic mutation which affect protein C activity. A severe recessive form may result in massive thrombosis fatal to the patient.

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29 results for "Coagulation Factor XIV/Protein C" in Products

29 results for "Coagulation Factor XIV/Protein C" in Products

Coagulation Factor XIV/Protein C Products

Coagulation Factor XIV / Protein C is a vitamin K-dependent serine protease synthesized in liver as a single-chain precursor. Present in plasma at 3 to 5 mg/L, protein C plays a key role in anticoagulation. Physiologically, the inactive forms of protein C are converted to the active form by thrombin, which releases the activation peptide. The active protein C cleaves factor VIIIa and Va to inactivate them. This anticoagulation activity can be enhanced by a presence of a cofactor such as protein S.

In hereditary thrombophilia, Coagulation Factor XIV /protein C deficiency is caused by a genetic mutation which affect protein C activity. A severe recessive form may result in massive thrombosis fatal to the patient.

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Applications: EnzAct
Applications: EnzAct
Applications: AC
Applications: EnzAct
Applications: IHC
Reactivity: Human
Applications: IHC, WB, ICC/IF
Reactivity: Human, Mouse, Rat

Recombinant Monoclonal Antibody

Applications: ELISA, NULL
Applications: ELISA, NULL
Catalog #: H00005624-T01
Applications: WB
Applications: ELISA
Reactivity: Human
Applications: ELISA
Reactivity: Human
Applications: ELISA
Reactivity: Human
Applications: WB, IP
Reactivity: Mouse
Applications: WB, IP
Reactivity: Human
Applications: WB
Reactivity: Mouse
Applications: WB
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: ELISA
Reactivity: Human
Applications: ELISA
Reactivity: Human
Applications: ELISA
Reactivity: Human
Applications: ELISA
Reactivity: Human
Applications: ELISA
Reactivity: Human
Applications: ELISA
Reactivity: Human
Applications: ELISA
Reactivity: Human
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