Human CRHBP Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB2796
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 Clone # 395108
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human CRHBP
Tyr25-Leu322
Accession # P24387
Tyr25-Leu322
Accession # P24387
Specificity
Detects human CRHBP in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse CRHBP is observed.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Applications for Human CRHBP Antibody
Application
Recommended Usage
Western Blot
1 µg/mL
Sample: Recombinant Human CRHBP
Sample: Recombinant Human CRHBP
Reviewed Applications
Read 4 reviews rated 4 using MAB2796 in the following applications:
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: CRHBP
Human CRHBP is a 37 kDa secreted glycoprotein that likely serves to regulate corticotrophin releasing hormone (CRH) availability to the adrenal. In human, CRHBP complexes with CRH to form a circulating 41 kDa complex. In rodent and horse, this complex is restricted to the CNS. Human CRHBP is synthesized as a 322 amino acid (aa) precursor that contains a 24 aa signal sequence and a 298 aa mature region. The mature region contains one potential CUB domain and five intrachain disulfide bonds. Human mature CRHBP shares 87% and 84% sequence identity with mouse and equine CRHBP, respectively.
Long Name
Corticotropin Releasing Hormone Binding Protein
Alternate Names
CRFBP
Entrez Gene IDs
1393 (Human)
Gene Symbol
CRHBP
UniProt
Additional CRHBP Products
Product Documents for Human CRHBP Antibody
Product Specific Notices for Human CRHBP Antibody
For research use only
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