Human CXCR4 Fluorescein-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB170F
Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Human
Cited:
Human
Applications
Validated:
Flow Cytometry
Cited:
Flow Cytometry
Label
Fluorescein (Excitation = 488 nm, Emission = 515-545 nm)
Antibody Source
Monoclonal Mouse IgG2A Clone # 12G5
Product Specifications
Immunogen
CP-MAC-infected SUP-T1 human T cell lymphoblastic lymphoma line
Accession # P61073
Accession # P61073
Specificity
Detects human CXCR4.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2A
Scientific Data Images for Human CXCR4 Fluorescein-conjugated Antibody
Detection of CXCR4 in Human Blood Lymphocytes by Flow Cytometry.
Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR4 Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB170F) and Mouse Anti-Human CD19 PE-conjugated Monoclonal Antibody (Catalog # FAB4867P). View our protocol for Staining Membrane-associated Proteins.
Detection of CXCR4 in Jurkat vs K562 cells by Flow Cytometry
Jurkat (filled histogram) vs K562 (open histogram) cells were stained with Mouse Anti-Human CXCR4 Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB170F). View our protocol for Staining Membrane-associated Proteins.Applications for Human CXCR4 Fluorescein-conjugated Antibody
Application
Recommended Usage
Flow Cytometry
10 µL/106 cells
Sample: see below
Sample: see below
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from ascites
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: CXCR4
CXCR4, also known as CD184, is a G-protein-linked seven transmembrane spanning receptor that binds stromal cell-derived factor-1 (SDF-1). CXCR4 acts as a co-factor for T-cell tropic HIV-1 and -2 viral entry into cells.
References
- Endres, M.J. et al. (1996) Cell 87:745.
Long Name
C-X-C Motif Chemokine Receptor 4
Alternate Names
CD184, D2S201E, FB22, Fusin, HM89, HSY3RR, LAP-3, LAP3, LCR1, LESTR, NPY3R, NPYRL, NPYY3R, WHIMS
Gene Symbol
CXCR4
UniProt
Additional CXCR4 Products
Product Documents for Human CXCR4 Fluorescein-conjugated Antibody
Product Specific Notices for Human CXCR4 Fluorescein-conjugated Antibody
For research use only
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