Human delta-Sarcoglycan Antibody

R&D Systems, part of Bio-Techne | Catalog # AF2778

R&D Systems, part of Bio-Techne
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AF2778
AF2778-SP
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

View all delta-Sarcoglycan Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human delta-Sarcoglycan isoform 1
Met1-Glu232
Accession # Q92629

Specificity

Detects human delta-Sarcoglycan in direct ELISAs and Western blots.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human delta-Sarcoglycan Antibody

Application
Recommended Usage

Immunohistochemistry

5-15 µg/mL
Sample: Immersion fixed frozen sections of human fetal brain

Western Blot

0.1 µg/mL
Sample: Recombinant Human delta-Sarcoglycan
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
Size / Price
Qty

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: delta-Sarcoglycan

Delta-sarcoglycan is one of six known sarcoglycans, which are type I ( alpha- and epsilon-) or type II ( beta-, gamma-, delta- or zeta-) transmembrane glycoproteins. Sarcoglycans associate in different combinations in a tissue-specific manner, to form heterotetrameric, pentameric and hexameric membrane glycoprotein complexes (SGC). SGC interacts laterally with the dystroglycan complex, and both complexes are components of the dystrophin-associated glycoprotein complex (DGC), which forms a link between the cytoskeleton and the extracellular matrix. Mutations in sarcoglycans are associated with recessive autosomally inherited muscular dystrophy.

Alternate Names

35DAG, CMD1L, DAGD, deltaSarcoglycan, LGMD2F, SGCD

Entrez Gene IDs

6444 (Human)

Gene Symbol

SGCD

UniProt

Q92629

Additional delta-Sarcoglycan Products

Product Documents for Human delta-Sarcoglycan Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human delta-Sarcoglycan Antibody

For research use only

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