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Human FCRL4/FcRH4 Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB24262

R&D Systems, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

CyTOF-ready, Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 580810

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human FCRL4/FcRH4
Gln16-Asp385
Accession # NP_112572

Specificity

Detects human FCRL4/FcRH4 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human FCRL1 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Human FCRL4/FcRH4 Antibody

Detection of FCRL4/FcRH4 antibody in RPMI 8226 Human Cell Line antibody by Flow Cytometry.

Detection of FCRL4/FcRH4 in RPMI 8226 Human Cell Line by Flow Cytometry.

RPMI 8226 human multiple myeloma cell line was stained with Mouse Anti-Human FCRL4/FcRH4 Monoclonal Antibody (Catalog # MAB24262, filled histogram) or isotype control antibody (Catalog # MAB002, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B).

Applications for Human FCRL4/FcRH4 Antibody

Application
Recommended Usage

CyTOF-ready

Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.

Flow Cytometry

2.5 µg/106 cells
Sample: RPMI 8226 human multiple myeloma cell line
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
Size / Price
Qty
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS and NaCl with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: FCRL4/FcRH4

Fc receptor-like 4 (FCRL4), also known as FcRH4 and IRTA1, is an Ig superfamily transmembrane protein that shares sequence homology with the classical Fc receptors. FCRL4 is preferentially expressed in B cells and contains three potential ITIM motifs in its cytoplasmic domain. The gene for FCRL4 is localized to the human chromosome 1q21‑23 region, a hotspot for translocation events.

Long Name

Fc Receptor-like protein 4

Alternate Names

CD307d, FcRH4, IGFP2, IRTA1

Entrez Gene IDs

83417 (Human)

Gene Symbol

FCRL4

UniProt

Additional FCRL4/FcRH4 Products

Product Documents for Human FCRL4/FcRH4 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human FCRL4/FcRH4 Antibody

For research use only

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