Human/Mouse SDPR Antibody

R&D Systems, part of Bio-Techne | Catalog # AF5759

R&D Systems, part of Bio-Techne
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AF5759
AF5759-SP
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Human, Mouse

Applications

Validated:

Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

View all SDPR Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human SDPR
Gly2-Val180
Accession # O95810

Specificity

Detects human and mouse SDPR in Western blots.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Human/Mouse SDPR Antibody

Detection of Human and Mouse SDPR antibody by Western Blot.

Detection of Human and Mouse SDPR by Western Blot.

Western blot shows lysates of human heart and mouse lung tissue. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human/Mouse SDPR Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5759) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF019). A specific band was detected for SDPR at approximately 70 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8.

Applications for Human/Mouse SDPR Antibody

Application
Recommended Usage

Western Blot

1 µg/mL
Sample: Human heart and mouse lung tissue

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: SDPR

SDPR (Serum deprivation response gene; also SDR and PS-p68) is a 68‑70 kDa member of the PTRF/SDPR family of proteins. It is expressed in striated muscle, platelets, and fibroblasts, and is cytosolic in location. SDPR is known to bind phosphatidylserine and form complexes with both PKC alpha and PTRF, targeting them to caveolae. Human SDPR is 425 amino acids (aa) in length. It contains an N-terminal acetylglycine, three coiled-coil regions (aa 61‑82, 125‑154, and 210‑268), and two serine phosphorylation sites at positions 287 and 293. Over aa 1‑180, human SDPR shares 91% aa identity with mouse SDPR.

Long Name

Serum Deprivation Response [Phosphatidylserine Binding Protein]

Alternate Names

PS-p68, SDR

Entrez Gene IDs

8436 (Human); 20324 (Mouse); 316384 (Rat)

Gene Symbol

CAVIN2

UniProt

O95810 (Human)

Additional SDPR Products

Product Documents for Human/Mouse SDPR Antibody

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human/Mouse SDPR Antibody

For research use only

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