Human SOX17 NorthernLights™ NL557-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # NL1924R
Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Human
Cited:
Human, Mouse
Applications
Validated:
Immunocytochemistry
Cited:
Immunocytochemistry, Immunohistochemistry, Immunohistochemistry-Frozen
Label
NL557 (Excitation = 557 nm, Emission = 574 nm)
Antibody Source
Polyclonal Goat IgG
Product Specifications
Specificity
Detects human SOX17 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) SOX2, rhSOX6, and rhSOX15 is observed.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Applications for Human SOX17 NorthernLights™ NL557-conjugated Antibody
Application
Recommended Usage
Immunocytochemistry
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.
Background: SOX17
SOX17 is a member of the SOX family of transcription factors that bind DNA via a high mobility group (HMG) domain. SOX17 is suggested to play an important role in endoderm development (1, 2). In Western blot, AF1924 detects a 60 kDa band of endogenous SOX17 which is higher than predicted molecular weight but consistent with the current literature (3).
References
- Kanai-Azuma, M. et al. (2002) Development 129:2367.
- Katoh, M. et al. (2002) Int. J. Mol. Med. 9:153.
- Sohn, J. et al. (2006) J. Neuroscience 26:9722.
Long Name
Transcription Factor SOX17
Alternate Names
FLJ22252, SRY (sex determining region Y)-box 17, SRY-related HMG-box transcription factor SOX17, transcription factor SOX-17, VUR3
Entrez Gene IDs
64321 (Human)
Gene Symbol
SOX17
UniProt
Additional SOX17 Products
Product Documents for Human SOX17 NorthernLights™ NL557-conjugated Antibody
Product Specific Notices for Human SOX17 NorthernLights™ NL557-conjugated Antibody
For research use only
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