Detects human TGF-beta RII in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant mouse (rm) TGF‑ beta RII and less than 1% cross-reactivity with recombinant human TGF-beta RIII and rmTGF-beta RI is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Human TGF-beta RII APC-conjugated Antibody

Detection of TGF-beta RII in Human Blood Lymphocytes by Flow Cytometry.

Human peripheral blood lymphocytes were stained with Goat Anti-Human TGF-beta RII APC-conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB2411A, filled histogram) or isotype control antibody (Catalog # IC108A, open histogram). View our protocol for Staining Membrane-associated Proteins.

Applications for Human TGF-beta RII APC-conjugated Antibody

Application

Recommended Usage

Flow Cytometry

10 µL/10⁶ cells
Sample: Human peripheral blood lymphocytes

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 4 using FAB2411A in the following applications:

Flow Cytometry (1 Review)

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.

12 months from date of receipt, 2 to 8 °C as supplied.

Background: TGF-beta RII

TGF betaRII is a membrane bound serine/threonine kinase. Upon ligand binding, TGF beta RII interacts with TGF betaRI to form the heteromeric signaling complex thattransduces TGF beta signals. A splice variant of the type II receptor, TGF betaRIIb, containing a 25 amino acid residue insertion near the Nterminus of the mature protein has also been described.

Long Name

Transforming Growth Factor beta Receptor II

Alternate Names

TGF-bRII, TGFbetaRII, TGFBR2

Entrez Gene IDs

7048 (Human); 21813 (Mouse)

Gene Symbol

TGFBR2

UniProt

P37173.2

Additional TGF-beta RII Products

Product Documents for Human TGF-beta RII APC-conjugated Antibody

Product Datasheets

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COA

SDS

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Product Specific Notices for Human TGF-beta RII APC-conjugated Antibody

For research use only

Citations
Reviews

Spectra Viewer
Flow Cytometry

Human TGF-beta RII APC-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB2411A

Key Product Details

Species Reactivity

Validated:

Cited:

Applications