ICAT/CTNNBIP1 Antibody (SR1112)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22453

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22453-100ul
NBP3-22453-50ul
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1112

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ICAT Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human ICAT/CTNNBIP1 (Uniprot #: Q9NSA3)

Specificity

Detects endogenous levels of total ICAT/CTNNBIP1

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

12 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ICAT/CTNNBIP1 Antibody (SR1112)

Western Blot: ICAT/CTNNBIP1 Antibody (SR1112) [NBP3-22453] -

Western Blot: ICAT/CTNNBIP1 Antibody (SR1112) [NBP3-22453] - Western blot analysis using NBP3-22453 in 293T cell lysate.

Applications for ICAT/CTNNBIP1 Antibody (SR1112)

Application
Recommended Usage

Flow Cytometry

1:50

Immunoprecipitation

1:50

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ICAT

CTNNBIP1, or Beta-catenin-interacting protein 1, consists of a short 81 amino acid isoform that is approximately 9 kDa, and is involved in the negative regulation of the Wnt signaling pathway, and it also prevents CTNNB1 and TCF from interacting. Current research is being conducted on CTNNBIP1 and a number of diseases to determine the relationship between the two. Some of these disorders and diseases include: actinic cheilitis, nasopharyngitis, adenomatous polyposis coli, gastric cancer, cheilitis, esophagitis, esophageal squamous cell carcinoma, laryngitis, desmoid tumor, hepatocellular carcinoma, acute lymphoblastic leukemia, medulloblastoma, malignant glioma, duodenitis, wilms tumor, endometrial carcinoma, and polyposis. CTNNBIP1 is linked to the Wnt signaling pathway, where it interacts with JUP, CTNNB1, BEND5, CASP4, and CPVL.

Long Name

Beta-Catenin-Interacting Protein

Alternate Names

CTNNBIP1

Gene Symbol

CTNNBIP1

Additional ICAT Products

Product Documents for ICAT/CTNNBIP1 Antibody (SR1112)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ICAT/CTNNBIP1 Antibody (SR1112)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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