ICAT: Proteins and Enzymes
Human ICAT is a physiological inhibitor of the beta-catenin/Wnt signaling pathway that is found in both cytosol and nucleus. The molecule contains two domains, an alpha-helical N-terminal region, and an acidic, extended C-terminal region. The alpha-helical region binds to beta-Catenin, displacing CBP/p300, while the acidic C-terminus blocks Tcf interaction. Human ICAT is 97% aa identical to both mouse and bovine ICAT.
2 results for "ICAT Proteins and Enzymes" in Products
2 results for "ICAT Proteins and Enzymes" in Products
ICAT: Proteins and Enzymes
Human ICAT is a physiological inhibitor of the beta-catenin/Wnt signaling pathway that is found in both cytosol and nucleus. The molecule contains two domains, an alpha-helical N-terminal region, and an acidic, extended C-terminal region. The alpha-helical region binds to beta-Catenin, displacing CBP/p300, while the acidic C-terminus blocks Tcf interaction. Human ICAT is 97% aa identical to both mouse and bovine ICAT.
| Applications: | PAGE |
![SDS-PAGE: Recombinant Human ICAT/CTNNBIP1 His Protein [NBP1-45266]](https://resources.bio-techne.com/images/products/ICAT-CTNNBIP1-Protein-SDS-Page-NBP1-45266-img0002.jpg "SDS-PAGE: Recombinant Human ICAT/CTNNBIP1 His Protein [NBP1-45266]")
| Applications: | AC |