Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

PE (Excitation = 488 nm, Emission = 575 nm)

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 2639B

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all IL-15R alpha Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line, NS0-derived human IL-15R alpha
Met1-Lys173
Accession # NP_751951

Specificity

Detects human IL-15R alpha in direct ELISAs.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IL-15R alpha Antibody (2639B) [PE]

Detection of IL-15R alpha in Human PBMC Monocytes by Flow Cytometry.

Human PBMC were stained with (A) Rabbit Anti-Human IL-15R alpha PE-conjugated Monoclonal Antibody (Catalog # FAB10900P) or (B) Rabbit IgG Control (IC1050P) and Mouse Anti-Human CD14 APC-conjugated Monoclonal Antibody (FAB3832A). Staining was performed using our Staining Membrane-associated Proteins protocol.

Detection of IL-15R alpha in Human PBMC Monocytes by Flow Cytometry.

Human PBMC were stained with (A) Rabbit Anti-Human IL-15R alpha PE-conjugated Monoclonal Antibody (Catalog # FAB10900P) or (B) Rabbit IgG Control (IC1050P) and Mouse Anti-Human CD14 APC-conjugated Monoclonal Antibody (FAB3832A). Staining was performed using our Staining Membrane-associated Proteins protocol.

Applications for IL-15R alpha Antibody (2639B) [PE]

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from cell culture supernatant

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: IL-15R alpha

IL15RA is a gene that codes for a protein that is a high-affinity receptor for interleukin-15, and can signal in both cis and trans to neighboring IL2RG-expressing cells, but the expression of different isoforms may interfere with this signal transduction, as isoforms 5-8 do not bind to IL15. The isoforms are all highly expressed in the brain, with isoform 1 being the longest with a 267 amino acid chain and a weight of approximately 28 kDa. Current studies are being done on several diseases and disorders relating to this gene including lymphoma, systemic lupus erythematosus, anemia, inflammatory bowel disease, leukemia, bronchiolitis, rheumatoid arthritis, hepatitis B, gingivitis, lung cancer and Alzheimer's disease. IL15Ra has also been shown to have interactions with SYK, IL2RB, TRAF2, and AXL in pathways such as the IL-15 signlaing, TCR signaling, and IgA production pathways.

Long Name

Interleukin 15 Receptor alpha

Alternate Names

CD215, IL-15 R alpha, IL-15Ra, IL15 R alpha, IL15RA

Additional IL-15R alpha Products

Product Documents for IL-15R alpha Antibody (2639B) [PE]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for IL-15R alpha Antibody (2639B) [PE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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