IL-15R alpha: Proteins and Enzymes
IL-15Ra (Interleukin 15 Receptor alpha), also known as CD215, is a transmembrane glycoprotein that plays an important role in NK and CD8+ memory T cell homeostasis and activation. It transmits IL-15 induced signals and additionally interacts with a complex of IL-2Rβ and the common gamma chain (γc) which are also subunits of the IL-2 receptor complex.
In transpresentation, IL-15/IL-15Ra complexes are expressed on the surface of one cell and interact with complexes of IL-2Rb/gc on adjacent cells. IL-15/IL-15Ra complexes can transmit reverse signaling that promotes adhesion and activation of the IL-15/IL-15Ra expressing cells. Shed soluble forms of IL-15Ra retain the ability to bind tightly to IL-15 and can inhibit IL-15 bioactivity.
Products:
5 results for "IL-15R alpha Proteins and Enzymes" in Products
5 results for "IL-15R alpha Proteins and Enzymes" in Products
IL-15R alpha: Proteins and Enzymes
IL-15Ra (Interleukin 15 Receptor alpha), also known as CD215, is a transmembrane glycoprotein that plays an important role in NK and CD8+ memory T cell homeostasis and activation. It transmits IL-15 induced signals and additionally interacts with a complex of IL-2Rβ and the common gamma chain (γc) which are also subunits of the IL-2 receptor complex.
In transpresentation, IL-15/IL-15Ra complexes are expressed on the surface of one cell and interact with complexes of IL-2Rb/gc on adjacent cells. IL-15/IL-15Ra complexes can transmit reverse signaling that promotes adhesion and activation of the IL-15/IL-15Ra expressing cells. Shed soluble forms of IL-15Ra retain the ability to bind tightly to IL-15 and can inhibit IL-15 bioactivity.
Products:
| Source: | NS0 |
| Accession #: | Q60819 |
| Applications: | BA |
| Source: | HEK293 |
| Accession #: | Q13261 |
| Applications: | BA |
| Source: | Sf 21 (baculovirus) |
| Accession #: | EAW86418 |
| Applications: | BA |
Biotinylated
| Source: | CHO |
| Accession #: | Q13261.1 |
| Applications: | BA |
Biotinylated
| Source: | CHO |
| Accession #: | Q13261.1 |
| Applications: | BA, Bind |
