IL-17/IL-17A Antibody (CL10252) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-07997

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (93%), Rat (93%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL10252

Format

BSA Free

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all IL-17/IL-17A Antibodies »

Product Specifications

Immunogen

This antibody was developed using a synthetic peptide derived from Q16552, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for IL-17/IL-17A Antibody (CL10252) - BSA Free

Immunohistochemistry-Paraffin: IL-17/IL-17A Antibody (CL10252) [NBP3-07997]

Immunohistochemistry-Paraffin: IL-17/IL-17A Antibody (CL10252) [NBP3-07997]

Immunohistochemistry-Paraffin: IL-17/IL-17A Antibody (CL10252) [NBP3-07997] - Staining of human rectum shows moderate cytoplasmic positivity in lymphoid cells.
Immunohistochemistry-Paraffin: IL-17/IL-17A Antibody (CL10252) [NBP3-07997]

Immunohistochemistry-Paraffin: IL-17/IL-17A Antibody (CL10252) [NBP3-07997]

Immunohistochemistry-Paraffin: IL-17/IL-17A Antibody (CL10252) [NBP3-07997] - Staining of human kidney shows no positivity in cells in tubules as expected.
Immunohistochemistry-Paraffin: IL-17/IL-17A Antibody (CL10252) [NBP3-07997]

Immunohistochemistry-Paraffin: IL-17/IL-17A Antibody (CL10252) [NBP3-07997]

Immunohistochemistry-Paraffin: IL-17/IL-17A Antibody (CL10252) [NBP3-07997] - Staining of human lymph node shows moderate cytoplasmic positivity in a subset of lymphoid cells.
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Applications for IL-17/IL-17A Antibody (CL10252) - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, containing 40% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-17/IL-17A

Interleukin 17 (IL-17) is a pro-inflammatory cytokine produced by TCRalpha/beta+ CD4 CD8 thymocytes, as well as by activated CD4+ and CD4+ CD45RO+ memory T cells (1). IL-17 stimulates the expression of TNFalpha, IL-1 beta, IL-6, and IL-8 (2). In addition, IL-17 is involved in the induction of inducible nitric oxide synthase and cyclooxygenase 2 in chondrocytes (3). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis (4).

Long Name

Interleukin 17

Alternate Names

CTLA-8, CTLA8, IL-17A, IL17, IL17A

Gene Symbol

IL17A

Additional IL-17/IL-17A Products

Product Documents for IL-17/IL-17A Antibody (CL10252) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IL-17/IL-17A Antibody (CL10252) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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