IL-3R alpha/CD123 Antibody (107D2.08)

Novus Biologicals, part of Bio-Techne | Catalog # DDX0300P-100

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Canine

Cited:

Human

Applications

Validated:

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 107D2.08

Concentration

0.5 mg/ml

View all IL-3R alpha Antibodies »

Product Specifications

Immunogen

IL3R Alpha/ CD123 was used as immunogen.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for IL-3R alpha/CD123 Antibody (107D2.08)

Immunohistochemistry: IL-3R alpha/CD123 Antibody (107D2.08) [DDX0300P-100]

Immunohistochemistry: IL-3R alpha/CD123 Antibody (107D2.08) [DDX0300P-100]

Immunohistochemistry: IL-3 R alpha/CD123 Antibody (107D2.08) [DDX0300P-100] - IHC staining of Bouin Paraffin section ofhuman invasive breast tumor with107D2.08 (DAB brown)
Flow Cytometry: IL-3R alpha/CD123 Antibody (107D2.08) [DDX0300P-100]

Flow Cytometry: IL-3R alpha/CD123 Antibody (107D2.08) [DDX0300P-100]

Flow Cytometry: IL-3 R alpha/CD123 Antibody (107D2.08) [DDX0300P-100] - Facs staining of CD11c-sorted tonsillar cells
Immunohistochemistry-Paraffin: IL-3R alpha/CD123 Antibody (107D2.08) [DDX0300P-100]

Immunohistochemistry-Paraffin: IL-3R alpha/CD123 Antibody (107D2.08) [DDX0300P-100]

Immunohistochemistry-Paraffin: IL-3 R alpha/CD123 Antibody (107D2.08) [DDX0300P-100] - Paraffin embedded breast cancer tissue sections
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Applications for IL-3R alpha/CD123 Antibody (107D2.08)

Application
Recommended Usage

Flow Cytometry

1:10-1:1000

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Immunoprecipitation

1:10-1:500

Western Blot

1:100-1:2000

Formulation, Preparation, and Storage

Purification

Ion exchange chromatography

Formulation

Tris-NaCl (pH 8.0)

Preservative

No Preservative

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: IL-3R alpha

IL3RA (CD123) is a member of the immunoglobulin superfamily that is expressed on hematopoietic progenitors, basophils, mast cells, and megakaryocytes. This transmembrane glycoprotein can bind IL3 with low affinity but cannot transduce signals without association with additional protein partners. CD123 can complex with either common beta chain (CDw131) or the IL3RB chain to form high affinity heterodimeric IL3 receptors. CDw131 can complex with the Alpha subunits of the mouse IL3R, IL5R and GMCSFR to form high affinity receptors, while the IL3RB subunit is specific for IL3 but binds with low affinity. IL3 binding to the receptor complex can induce proliferation and differentiation of hematopoietic cells. It is present in Hematopoietic progenitors, basophils, mast cells and megakaryocytes.

Long Name

Interleukin 3 Receptor alpha

Alternate Names

CD123, IL-3 R alpha, IL-3Ra, IL3R alpha, IL3RA

Gene Symbol

IL3RA

Additional IL-3R alpha Products

Product Documents for IL-3R alpha/CD123 Antibody (107D2.08)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for IL-3R alpha/CD123 Antibody (107D2.08)

This product is manufactured by Eurobio Scientific (formerly Dendritics) and distributed by Novus Biologicals.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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