IL-3R alpha/CD123 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16953

Novus Biologicals, part of Bio-Techne
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NBP2-16953
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all IL-3R alpha Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human IL-3R alpha/CD123. The exact sequence is proprietary.

Localization

Membrane; Single-pass type I membrane protein

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

43 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for IL-3R alpha/CD123 Antibody

Western Blot: IL-3R alpha/CD123 Antibody [NBP2-16953]

Western Blot: IL-3R alpha/CD123 Antibody [NBP2-16953]

Western Blot: IL-3 R alpha/CD123 Antibody [NBP2-16953] - IL3 Receptor alpha antibody [N2C2], Internal detects IL3 Receptor alpha protein by western blot analysis. THP-1 whole cell extracts (30 ug), non-transfected (-) and IL3 Receptor alpha-transfected (+) 293T whole cell extracts (5 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with IL3 Receptor alpha antibody diluted by 1:1000
Immunohistochemistry-Paraffin: IL-3R alpha/CD123 Antibody [NBP2-16953]

Immunohistochemistry-Paraffin: IL-3R alpha/CD123 Antibody [NBP2-16953]

Immunohistochemistry-Paraffin: IL-3 R alpha/CD123 Antibody [NBP2-16953] - Human esophageal cancer. IL3 Receptor alpha antibody [N2C2], Internal diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
Immunohistochemistry-Paraffin: IL-3R alpha/CD123 Antibody [NBP2-16953]

Immunohistochemistry-Paraffin: IL-3R alpha/CD123 Antibody [NBP2-16953]

Immunohistochemistry-Paraffin: IL-3 R alpha/CD123 Antibody [NBP2-16953] - Human breast cancer, using IL3 Receptor alpha antibody at 1:250 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

Applications for IL-3R alpha/CD123 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: IL-3R alpha

The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. [provided by RefSeq]

Long Name

Interleukin 3 Receptor alpha

Alternate Names

CD123, IL-3 R alpha, IL-3Ra, IL3R alpha, IL3RA

Gene Symbol

IL3RA

UniProt

P26951

Additional IL-3R alpha Products

Product Documents for IL-3R alpha/CD123 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for IL-3R alpha/CD123 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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