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Key Product Details

Species Reactivity

Human

Applications

CyTOF-ready, Flow Cytometry

Label

mFluor Violet 500 SE (Excitation = 410 nm, Emission = 501 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # 600007

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human LILRA2/CD85h/ILT1
Pro17-Ser437
Accession # Q8N149

Specificity

Detects human LILRA2/CD85h/ILT1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) ILT2, 3, 4, 5, rhLIR6, or rhLIR8 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for ILT1/CD85h/LILRA2 Antibody (600007) [mFluor Violet 500 SE]

Application
Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: LILRA2/CD85h/ILT1

LILRA2, also known as Leukocyte immunoglobulin-like receptor subfamily A member 2, has a 483 amino acid long isoform that is 53 kDa and a short 466 amino acid isoform that is 51 kDa, acts as an activating receptor for eosinophils that elicited the release of cytotoxic granule proteins, de novo lipid mediator generation, and cytokine release through vesicular transport, but does not bind class I MHC antigens. Studies are being performed in relation to this protein and several diseases and disorders including leprosy, microscopic polyangiitis, systemic lupus, erythematosus, lupus erythematosus, hepatitis c, and hepatitis b. This protein has been shown to interact with EWSR1 and USP46 proteins in osteoclast differentiation, defense response, and signal transduction pathways.

Long Name

Leukocyte Immunoglobulin-like Receptor, Subfamily A (with TM domain), Member 2

Alternate Names

CD85h, ILT1, LIR7

Gene Symbol

LILRA2

Additional LILRA2/CD85h/ILT1 Products

Product Documents for ILT1/CD85h/LILRA2 Antibody (600007) [mFluor Violet 500 SE]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ILT1/CD85h/LILRA2 Antibody (600007) [mFluor Violet 500 SE]

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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