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ILT2/CD85j/LILRB1 Antibody (PSH04-59)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-32537

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-32537

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # PSH04-59

Concentration

1 mg/ml

Product Specifications

Immunogen

Recombinant protein within human ILT2/CD85j/LILRB1 aa 1-461 / 650. (Uniprot: Q8NHL6)

Localization

Cell membrane; Secreted.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

71 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for ILT2/CD85j/LILRB1 Antibody (PSH04-59)

ILT2/CD85j/LILRB1 Antibody (PSH04-59)

Western Blot: ILT2/CD85j/LILRB1 Antibody (PSH04-59) [NBP3-32537]

Western Blot: ILT2/CD85j/LILRB1 Antibody (PSH04-59) [NBP3-32537] - Western blot analysis of ILT2/CD85j/LILRB1 on different lysates with Rabbit anti-ILT2/CD85j/LILRB1 antibody (NBP3-32537) at 1/1,000 dilution.

Lane 1: Raji cell lysate
Lane 2: Daudi cell lysate
Lane 3: THP-1 cell lysate
Lane 4: A431 cell lysate (negative)
Lane 5: K-562 cell lysate (negative)

Lysates/proteins at 20 ug/Lane.

Predicted band size: 71 kDa
Observed band size: 120 kDa

Exposure time: 1 minute; ECL;

4-20% SDS-PAGE gel.

Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (NBP3-32537) at 1/1,000 dilution was used in 5% NFDM/TBST at 4 overnight. Goat Anti-Rabbit IgG - HRP Secondary Antibody at 1/50,000 dilution was used for 1 hour at room temperature.

Applications for ILT2/CD85j/LILRB1 Antibody (PSH04-59)

Application
Recommended Usage

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH7.4), 0.1% BSA and 40% Glycerol

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LILRB1/CD85j/ILT2

LILRB1 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Long Name

Leukocyte Immunoglobulin-like Receptor, Subfamily A (with TM domain), Member 1

Alternate Names

CD85j, ILT2, LIR1, MIR7

Gene Symbol

LILRB1

Additional LILRB1/CD85j/ILT2 Products

Product Documents for ILT2/CD85j/LILRB1 Antibody (PSH04-59)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ILT2/CD85j/LILRB1 Antibody (PSH04-59)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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