Key Product Details

Species Reactivity

Human

Applications

CyTOF-ready, Immunohistochemistry, Immunoprecipitation, Intracellular Staining by Flow Cytometry, Western Blot

Label

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # 110316

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MMP-10 Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human MMP-10
Phe99-Cys476
Accession # P09238

Specificity

Detects the pro and active forms of human MMP-10 in direct ELISAs Western blots. In direct ELISAs and Western blots, approximately 10‑50% cross‑reactivity with recombinant human (rh) MMP-3 and no cross-reactivity with rhMMP-1, -2, -7, -8, -9, -12, or -13 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for MMP-10 Antibody (110316) [DyLight 488]

Application
Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Intracellular Staining by Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: MMP-10

Matrix metalloproteinases belong to a family of proteases that are essential for the breakdown of extracellular matrix (ECM), thus they play an important role in apoptosis, and tumor cell growth, invasion, metastasis, as well as in angiogenesis and wound healing. Most of the MMP's contain a common domain structures, which include a signal sequence, a propeptide, a catalytic domain and a hemopexin-like (Hpx) domain. MMP10 belongs to the Stromelysin group of proteases. Stromelysins degrade ECM proteoglycans, laminin, fibronectin and gelatin.

Long Name

Matrix Metalloproteinase 10

Alternate Names

MMP10, Stromelysin 2

Gene Symbol

MMP10

Additional MMP-10 Products

Product Documents for MMP-10 Antibody (110316) [DyLight 488]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for MMP-10 Antibody (110316) [DyLight 488]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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