MMP-3 Antibody (MMP3/1994R) [mFluor Violet 450 SE] [NBP3-08627MFV450] - Vial of mFluor Violet 450 conjugated antibody. mFluor Violet 450 is optimally excited at 406 nm by the Violet laser (405 nm) and has an emission maximum of 445 nm.

Applications for MMP-3 Antibody (MMP3/1994R) [mFluor Violet 450 SE]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: MMP-3

Effective inhibitors of matrix metalloproteinases (MMPs), a family of connective tissue-degrading enzymes, could be useful for the treatment of diseases such as cancer, multiple sclerosis, and arthritis (1). Matrix metalloproteinase-3 (MMP-3) is a protein involved in tumor invasion and metastasis. MMP3 (stromelysin) is a secreted metalloprotease with a wide range of substrate specificities. MMP3 is synthesized in a preproenzyme form with a calculated size of 54 kDa and a 17-amino acid long signal peptide. Data indicate that the expression and the possible involvement of secreted metalloproteases in tumorigenesis result from a specific interaction between the transforming factor and the target cell, which may vary in different species (2). In neural studies, matrix metalloproteinase-3 (MMP-3) was newly induced and activated in stressed dopamine cells, and the active form of MMP-3 (actMMP-3) was released into the medium. The released actMMP-3, as well as catalytically active recombinant MMP-3 (cMMP-3) led to microglial activation and superoxide generation in microglia and enhanced DA cell death. (3).

Long Name

Matrix Metalloproteinase 3

Alternate Names

MMP3, Stromelysin 1

Gene Symbol

MMP3

Additional MMP-3 Products

Product Documents for MMP-3 Antibody (MMP3/1994R) [mFluor Violet 450 SE]

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for MMP-3 Antibody (MMP3/1994R) [mFluor Violet 450 SE]

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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MMP-3 Antibody (MMP3/1994R) [mFluor Violet 450 SE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-08627MFV450

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

Concentration

View all MMP-3 Antibodies »

Product Specifications

Immunogen

Localization

Marker

Clonality

Host

Isotype

Scientific Data Images for MMP-3 Antibody (MMP3/1994R) [mFluor Violet 450 SE]

MMP-3 Antibody (MMP3/1994R) [mFluor Violet 450 SE] [NBP3-08627MFV450] -

Applications for MMP-3 Antibody (MMP3/1994R) [mFluor Violet 450 SE]

ELISA

Flow Cytometry

Western Blot

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: MMP-3

Long Name

Alternate Names

Gene Symbol

Additional MMP-3 Products

Product Documents for MMP-3 Antibody (MMP3/1994R) [mFluor Violet 450 SE]

Product Datasheets

COA

Certificate of Analysis

SDS

Product Specific Notices for MMP-3 Antibody (MMP3/1994R) [mFluor Violet 450 SE]