Mouse CRHBP Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB3087

R&D Systems, part of Bio-Techne
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MAB3087
MAB3087-SP
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Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2A Clone # 356803

View all CRHBP Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse CRHBP
Tyr25-Leu322
Accession # Q60571

Specificity

Detects mouse CRHBP in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross‑reactivity with recombinant human CRHBP is observed.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2A

Applications for Mouse CRHBP Antibody

Application
Recommended Usage

Western Blot

1 µg/mL
Sample: Recombinant Mouse CRHBP

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: CRHBP

Mouse CRHBP (Corticotrophin-Releasing Hormone Binding Protein) is a 37 kDa monomeric CRH-binding glycoprotein that is secreted by cells of the rodent adrenal medulla, cortical neurons and astrocytes, and prolactin positive cells of the pituitary. The mature molecule is 298 aa in length and contains six intrachain disulfide bonds. It binds CRH and CRH-like peptides, either serving as an antagonist for CRH binding to CRH receptor 1, or as a coreceptor for CRH binding to CRH receptor 2. Mature mouse CRHBP shares 94%, 87%, 85%, and 80% aa sequence identity with rat, human, canine and bovine CRHBP, respectively.

Long Name

Corticotropin Releasing Hormone Binding Protein

Alternate Names

CRFBP

Entrez Gene IDs

1393 (Human)

Gene Symbol

CRHBP

UniProt

Q60571

Additional CRHBP Products

Product Documents for Mouse CRHBP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Mouse CRHBP Antibody

For research use only

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